Alexa Fluor^™ 488 Anti-Human CD105 (MEM-226)

The antibody MEM-226 reacts with an extracellular epitope of CD105 (Endoglin), a 90 kDa type I homodimerizing membrane glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow; it is also present on syncytiotrophoblast on placenta throughout pregnancy. PRODUCT DETAILSClone: MEM-226Specificity: CD105Reactivity: Human, RatFormat: Alexa Fluor™ 488Isotype: Mouse IgG2aTested Dilution: 5 µL/TestApplication: FCStorage: 2-8°C protected from light.Do not freezeFormulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azideData Sheets: TDS | SDS RECOMMENDED USAGEFlow cytometry: The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests. REFERENCES Zhu Y, et al. 2003. Stroke 34:2483-8. Li C, et al. 2003. J Cell Sci 116:2677-85. Guo B, et al. 2004. Anticancer Res 24:1337-45. Warrington K, et al. 2005. Anticancer Res 25:1851-64. Piao M, et al. 2006. J Atheroscler Thromb 13:82-9. Schmidt D, et al. 2007. Circulation 116:I64-70. Asumda FZ, et al. 2011. BMC Cell Biol 12:44. Liang L, et al. 2021. Stem Cell Res Ther 12:87. Zhang J, et al. 2021. Front Cell Dev Biol 9:629274. Chang Y, et al. 2022. J Renin Angiotensin Aldosterone Syst 2022:1283729. For research use only. Not intended for use in diagnostic procedures. “Alexa Fluor“ is a trademark of Thermo Fisher Scientific Inc.