⚕️ RX | Librela for Dogs - Injectable Pain Medication For Dogs

Prescription required. A valid prescription is needed to dispense this medication. If your pet has not been examined by a veterinarian within the past 12 months, a current prescription will be required first. Need help? Request prescription assistance → Librela (bedinvetmab injection) is a prescription monoclonal antibody from Zoetis for the control of pain associated with osteoarthritis (OA) in dogs. Bedinvetmab targets and neutralizes nerve growth factor (NGF), a key driver of OA pain, and is given as a once-monthly subcutaneous injection at a minimum dose of 0.5 mg/kg (0.23 mg/lb). Key facts Active ingredient: Bedinvetmab, a canine anti-NGF monoclonal antibody. Species: Dogs only — not for use in cats. Use: Control of pain associated with osteoarthritis in dogs. Available sizes: 1 mL single-use vials in five strengths — 5, 10, 15, 20, and 30 mg/mL — matched to weight bands from 11 lb to 132.3 lb; sold per vial or in boxes of 6. Dosing: Once monthly by subcutaneous injection, administered by or on the order of a licensed veterinarian. Storage: Refrigerated — ships cold-chain in an insulated cooler with ice packs. How to use Librela is given as a subcutaneous injection once monthly, with the vial strength selected for your dog's body weight. Keep vials refrigerated until use and follow the injection and handling guidance from your veterinarian and your Smarty Vets consultation. Full effect may not be seen until after the second monthly dose, so give it time before judging response. Safety information Do not use in breeding, pregnant, or lactating dogs; not evaluated in dogs under 12 months of age. The most common side effects in field studies were urinary tract infections (11.1%), bacterial skin infections (8.1%), and dermatitis (7.4%); injection site reactions can also occur. Neurologic signs such as ataxia and seizures, as well as lethargy and appetite changes, have been reported post-approval — contact your veterinarian if you notice anything unusual. Not for use in humans. Pregnant and nursing women should take extreme care to avoid accidental self-injection. Frequently asked questions How does Librela work? Bedinvetmab binds and neutralizes nerve growth factor (NGF), which plays a central role in osteoarthritis pain signaling. Reducing NGF activity lessens pain, helping dogs move more comfortably. How fast does Librela work? Some dogs improve after the first injection, but the label notes effectiveness may not be achieved until after the second monthly dose. Is a prescription required for Librela? Yes. Librela requires a valid prescription from your veterinarian. First-time orders also require a Smarty Vets prescription consultation covering injection technique, safe handling, side effects, and cold-chain shipping — book your free consultation here. Refills can be ordered directly once your dog has been on Librela for at least 60 days without side effects: upload your prescription at checkout. How is Librela shipped? Librela must remain temperature-controlled, so it ships in an insulated cooler with ice packs via FedEx Priority Overnight. Cold-chain shipping is $60 per order regardless of the number of vials. What are common side effects of Librela? Urinary tract infections, bacterial skin infections, dermatitis, and injection site pain were most commonly reported in field studies. Report any unusual signs, including wobbliness or seizures, to your veterinarian promptly. Can cats receive Librela? No. Librela is labeled for dogs only. The feline counterpart is Solensia (frunevetmab), a monthly anti-NGF injection for cats with osteoarthritis pain. Cat owner? See Solensia (frunevetmab) monthly OA pain injection for cats.