Mitochondria Prime+™

Mitochondria Prime+ is a next-generation, systems-based mitochondrial healthspan formula delivering seven clinically targeted ingredients, including two Healthgevity-exclusive compounds, across the three foundational pillars of mitochondrial optimization: Power (cellular ATP production and energy metabolism), Protect (redox balance and endogenous antioxidant defense), and Renew (mitochondrial renewal, mitophagy-related pathways, and cellular longevity signaling), designed for practitioners seeking a comprehensive, evidence-grounded approach to cellular energy, healthy aging, cognitive clarity, muscle performance, and long-term mitochondrial vitality. Mitochondria are the cellular powerhouses that convert nutrients into ATP, the energy currency that fuels every biological process. They regulate oxidative stress, influence metabolic flexibility, and provide the cellular signaling environment required for tissue repair, immune function, and long-term resilience. With age, cumulative oxidative damage, high metabolic demand, environmental stress, and the declining efficiency of mitochondrial quality control processes including mitophagy (the cellular process of clearing damaged mitochondria), mitochondrial function progressively declines. The consequences show up across virtually every system simultaneously: reduced energy output, slower physical recovery, declining cognitive clarity, muscle weakness, and the broader pattern of accelerating biological aging that researchers increasingly attribute to mitochondrial dysfunction as a root cause rather than a downstream effect. Mitochondria Prime+ addresses this decline across all three mechanistic layers. Energy production is supported through Acetyl-L-Carnitine (fatty acid transport into mitochondria) and active Riboflavin-5-Phosphate (electron transport chain cofactor). Redox defense is addressed through Algevity marine algae extract (Nrf2 pathway and endogenous antioxidant upregulation), MitoPrime L-Ergothioneine (specialized cellular antioxidant with dedicated tissue transport), Astaxanthin (membrane-integrated antioxidant for mitochondrial membrane resilience), and Selenium as L-Selenomethionine (glutathione peroxidase enzyme support). Mitochondrial renewal is supported through Naturalin Pro, the centerpiece of the formula, a next-generation urolithin complex providing Urolithin A, Urolithin B, highly soluble ellagic acid, and Choline for both direct urolithin mitophagy signaling and precursor pathway support. Naturalin Pro and Algevity are both Healthgevity Exclusive ingredients, available only through Healthgevity and its authorized retailer network. At $124.99, Mitochondria Prime+ is the highest-tier product in the Healthgevity lineup and represents their most comprehensive single-formula approach to mitochondrial healthspan optimization. Key Benefits: Supports cellular energy production and mitochondrial efficiency via Acetyl-L-Carnitine and active Riboflavin Supports mitochondrial renewal and mitophagy-related pathways via Naturalin Pro urolithin complex Urolithin A supports mitophagy, the cellular process of clearing and renewing damaged mitochondria Urolithin B supports muscle protein signaling pathways alongside mitochondrial renewal Supports Nrf2-mediated endogenous antioxidant defense via Algevity marine algae extract MitoPrime L-Ergothioneine provides specialized cellular antioxidant support with dedicated tissue transport system Astaxanthin at 12 mg provides membrane-integrated antioxidant protection for mitochondrial membrane stability Selenium as L-Selenomethionine supports glutathione peroxidase and antioxidant enzyme systems Supports cognitive clarity, focus, and sustained mental energy Supports muscle performance, endurance, and physical recovery Supports redox balance and cellular resilience against age-related oxidative demand Naturalin Pro and Algevity are Healthgevity Exclusive ingredients Systems-based three-pillar approach covering Power, Protect, and Renew simultaneously What's Inside — Full Supplement Facts (per serving): Naturalin Pro — 700 mg (Healthgevity Exclusive) A next-generation urolithin-focused mitochondrial renewal complex providing Urolithin A, Urolithin B, highly soluble ellagic acid, and Choline. Urolithin A is the postbiotic compound produced from polyphenol-rich foods including pomegranates and berries that is most extensively studied for its role in supporting mitophagy, the cellular quality control process that clears damaged mitochondria and allows healthy mitochondrial populations to regenerate. Urolithin B provides complementary muscle protein signaling support, and highly soluble ellagic acid serves as an ellagitannin precursor to urolithin synthesis. Choline supports phospholipid synthesis for mitochondrial membrane support alongside the urolithin activity. Healthgevity Exclusive ingredient. Algevity Factor — 300 mg (Healthgevity Exclusive) A supercritical CO2 extract of Ulva lactuca, a marine green algae, selected for its cellular defense and resilience profile with particular relevance to Nrf2 pathway activation. Nrf2 (Nuclear factor erythroid 2-related factor 2) is the master transcription factor that activates the body's endogenous antioxidant defense network, upregulating the expression of antioxidant enzymes including superoxide dismutase, catalase, glutathione peroxidase, and heme oxygenase-1. By supporting these internal defense systems rather than simply adding exogenous antioxidants, Algevity supports the cellular environment needed for robust mitochondrial function from the inside out. Healthgevity Exclusive ingredient. Acetyl-L-Carnitine HCl — 750 mg The acetylated form of L-Carnitine that supports the transport of long-chain fatty acids across the inner mitochondrial membrane, where they undergo beta-oxidation for ATP production. Acetyl-L-Carnitine also supports neuronal energy metabolism, acetylcholine synthesis, and cognitive function, making it relevant for both physical performance and mental clarity. The acetyl group directly supports the acetyl-CoA pool that feeds the Krebs cycle for ATP generation. Riboflavin-5-Phosphate Sodium — 50 mg The active coenzyme form of Vitamin B2, serving as the precursor to FAD (flavin adenine dinucleotide) and FMN (flavin mononucleotide), the essential cofactors in Complexes I and II of the mitochondrial electron transport chain. Without adequate riboflavin-based cofactors, electron transport chain function is impaired and ATP production efficiency declines. As R5P rather than standard riboflavin, this is immediately bioavailable without the conversion step required by the free vitamin form. L-Ergothioneine as MitoPrime — 25 mg A unique diet-derived thiohistidine betaine antioxidant with a dedicated cellular transporter (OCTN1/SLC22A4) that enables it to accumulate specifically in tissues with high metabolic activity and oxidative demand, including the liver, red blood cells, kidneys, and mitochondria themselves. Unlike most antioxidants that distribute broadly, ergothioneine concentrates where oxidative stress is highest. MitoPrime is the registered trademark for the highest-purity L-Ergothioneine available, supporting mitochondrial integrity, cellular redox balance, and long-term cellular resilience. Astaxanthin — 12 mg A keto-carotenoid that uniquely integrates into both the inner and outer layers of cell membranes due to its amphiphilic molecular structure, positioning it at the site of mitochondrial membrane-based oxidative stress rather than remaining in the aqueous cellular environment. At 12 mg, Mitochondria Prime+ provides a meaningful therapeutic dose for membrane stability, mitochondrial resilience, and recovery from the elevated oxidative demands associated with physical activity, aging, and environmental stress. Selenium as L-Selenomethionine — 100 mcg The most bioavailable organic form of selenium, supporting the synthesis and activity of selenoprotein antioxidant enzymes, particularly glutathione peroxidase (GPx), thioredoxin reductase (TrxR), and selenoprotein P. These enzymes are central to cellular redox regulation, hydrogen peroxide neutralization, and the regeneration of glutathione in its reduced, active form. Adequate selenium status is essential for the endogenous antioxidant defense that Algevity supports through Nrf2 upregulation. Storage Store in a cool, dry place. Keep out of reach of children. Directions Take as directed on the product label or as recommended by your healthcare professional. Consistent daily use is recommended for progressive mitochondrial and cellular health support. Consult your healthcare professional before use if pregnant, nursing, taking medications, or have a medical condition. Healthgevity Mitochondria Prime+ is a practitioner-trusted next-generation mitochondrial healthspan supplement available at SOLUDE Wellness & Beauty. It contains Naturalin Pro 700 mg (Healthgevity Exclusive urolithin complex with Urolithin A, Urolithin B, highly soluble ellagic acid, and Choline), Algevity Factor 300 mg (Healthgevity Exclusive Ulva lactuca marine algae Nrf2 support), Acetyl-L-Carnitine HCl 750 mg, Riboflavin-5-Phosphate Sodium 50 mg, L-Ergothioneine (as MitoPrime) 25 mg, Astaxanthin 12 mg, and Selenium (as L-Selenomethionine) 100 mcg. It is designed to support cellular energy production and mitochondrial efficiency, mitochondrial renewal and mitophagy via urolithin A and B, Nrf2-mediated endogenous antioxidant defense, redox balance and cellular resilience, cognitive clarity and focus, muscle performance endurance and recovery, membrane stability via astaxanthin, and glutathione enzyme support via selenium. Three-pillar systems-based approach: Power, Protect, Renew. Naturalin Pro and Algevity are Healthgevity Exclusive ingredients. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.