EBAK 10MG TAB

EBAK 10MG TABLET ONLINE AT BEST PRICE IN PAKISTAN GENERIC: Ebastine 10mg MANUFACTURER: High-Q Pharma QUANTITY: Pack of 20 tablets INDICATION Ebak 10mg Tab is a second-generation, non-sedating antihistamine used for the relief of symptoms associated with seasonal allergic rhinitis (hay fever), perennial allergic rhinitis, and chronic idiopathic urticaria (hives). It effectively reduces sneezing, nasal discharge, nasal itching, watery eyes, and skin itching and redness without causing significant sedation or impairment. MECHANISM OF ACTION Ebastine is a selective and long-acting H1 histamine receptor antagonist. It competitively blocks histamine binding at peripheral H1 receptors on blood vessels, bronchi, and sensory nerve endings, preventing the vasodilation, increased capillary permeability, smooth muscle contraction, and nerve sensitization caused by histamine. Ebastine has minimal penetration of the blood-brain barrier, resulting in a low incidence of sedation. Its active metabolite, carebastine, has a prolonged half-life providing 24-hour allergy relief. DOSAGE AND ADMINISTRATION • Adults and adolescents above 12 years: 10mg once daily • Severe symptoms: 20mg once daily may be used • Children 6 to 11 years: 5mg once daily (lower strength formulation required) • Take with or without food; once-daily dosing provides all-day control • No dose adjustment needed in mild to moderate renal or hepatic impairment SIDE EFFECTS Common: • Headache • Dry mouth, somnolence (infrequent) • Nausea, abdominal pain • Dizziness Less common: • QT prolongation at high doses, particularly when combined with other QT-prolonging drugs • Hypersensitivity reactions including angioedema • Palpitations NOT RECOMMENDED IN • Known hypersensitivity to Ebastine • Concomitant use with strong CYP3A4 inhibitors (ketoconazole, erythromycin) increases QT risk; use with caution • Known QT prolongation or hypokalaemia • Not recommended in children under 2 years DRUG INTERACTIONS Ebastine is metabolized by CYP3A4. Strong CYP3A4 inhibitors such as ketoconazole and erythromycin significantly increase plasma Ebastine levels, raising the risk of QT prolongation. Ebastine should be used with caution alongside other QT-prolonging medications. Grapefruit juice may inhibit CYP3A4 and increase Ebastine exposure. STORAGE INSTRUCTIONS Store Ebak 10mg tablets at room temperature below 30°C. Protect from moisture and sunlight. Keep in original blister packaging. Store out of reach of children. WHERE TO BUY Buy Ebak 10mg Tab online from Dawa Healthcare Pharmacy for non-drowsy allergy relief in Pakistan. Check the Ebak 10mg Tab price in Pakistan and learn about Ebak 10mg Tab uses from our pharmacist team. Same-day delivery in Karachi. Nationwide delivery through Dawa Healthcare Pharmacy.