Cardio NAD+

Cardio NAD+ is an advanced multi-mechanism cardiovascular and cardiometabolic support formula combining eight clinically targeted ingredients, including NAD3, Niacinamide, PeptiPump, CoQ10 (as LEO-HB), Fucoidan, FitNox, Nattokinase (NSK-SD), and Citrus Bergamot, designed to comprehensively address the cellular, vascular, lipid, and hemodynamic dimensions of cardiovascular aging through a unified approach that supports NAD+ status, endothelial function, vascular elasticity, healthy blood flow and viscosity, healthy blood pressure, fibrinolytic activity, and balanced inflammatory and oxidative responses simultaneously. Cardiovascular aging is not one problem. It is the convergence of declining cellular energy capacity in cardiac tissue (driven by NAD+ depletion and mitochondrial dysfunction), endothelial dysfunction (loss of the protective glycocalyx lining of blood vessel walls), impaired vascular elasticity and blood flow mechanics (driven by fibrin accumulation and platelet aggregation), unfavorable lipid and metabolic biomarker changes, and increasing systemic oxidative and inflammatory burden. Most cardiovascular supplements address one or two of these dimensions. Cardio NAD+ was designed to address all of them simultaneously through a systems-based formulation that integrates the most novel, evidence-grounded cardiovascular ingredients available. The formula operates through four complementary dimensions. NAD+ and cellular energy are supported by NAD3 (Wasabi japonica extract, theacrine, and copper-niacin complex, the multi-mechanistic NAD+ support system that sustains NAD+ status by promoting both its synthesis and limiting its enzymatic degradation) alongside Niacinamide (200 mg) through the NAD+ salvage pathway for mitochondrial efficiency and cellular resilience. Endothelial and vascular function are supported by PeptiPump (bioactive plant-derived peptides from Nuritas proprietary technology supporting vascular health), Fucoidan from Undaria pinnatifida mekabu extract standardized to approximately 85% fucoidan for glycocalyx regeneration and endothelial lining support, and FitNox (a 250 mg nitric oxide-supporting botanical blend for vascular elasticity and endothelial function). Blood flow mechanics are addressed by Nattokinase NSK-SD (derived from fermented soy, supporting healthy fibrin turnover, blood viscosity, platelet activity, and circulation). Lipid and cardiometabolic balance are supported by Citrus Bergamot from Calabria, Italy, providing polyphenolic compounds for healthy cholesterol ratios, triglyceride levels, and oxidative balance. And cellular energy in cardiac tissue is further addressed by CoQ10 delivered through LEO-HB technology, an eco-friendly solid-solid technology that dramatically improves CoQ10 solubility and bioavailability over standard CoQ10 preparations. Three capsules daily. Refer to the product label for exact milligram supplement facts per ingredient. Nattokinase has fibrinolytic and anticoagulant activity. Consult your healthcare practitioner before use if taking blood-thinning medications including warfarin, aspirin, or antiplatelet agents. Key Benefits: Supports NAD+ status through synthesis promotion and degradation limitation via NAD3 Niacinamide 200 mg supports NAD+ salvage pathway, mitochondrial efficiency, and cellular resilience Supports endothelial function and vascular elasticity via PeptiPump bioactive peptides and FitNox nitric oxide support Supports glycocalyx regeneration and endothelial lining integrity via Fucoidan from Undaria pinnatifida Supports healthy fibrinolytic activity, blood viscosity, and platelet activity via Nattokinase NSK-SD Supports healthy blood pressure and circulation Supports healthy cholesterol ratios and triglyceride levels via Citrus Bergamot polyphenols CoQ10 via LEO-HB technology for dramatically enhanced solubility and bioavailability for cardiac energy support Supports balanced inflammatory response and oxidative balance Supports vascular aging biomarkers and healthy arterial function Supports cardiometabolic health and metabolic signaling Multi-mechanistic NAD3 addresses the root causes of declining cellular NAD+ status Eight-ingredient systems-based formula covering all major dimensions of cardiovascular aging What's Inside — Key Ingredients (per 3-capsule serving, refer to product label for exact mg): NAD3 (Wasabi japonica Extract, Theacrine, Copper-Niacin Complex) — NAD3 is a patented multi-mechanistic NAD+ support system that addresses declining NAD+ from multiple directions simultaneously. The Wasabi japonica extract component provides isothiocyanates that support sirtuin activity and cellular resilience pathways. Theacrine provides complementary energy, cognitive clarity, and anti-fatigue support through adenosine receptor modulation without the desensitization associated with caffeine. The copper-niacin complex supports NAD+ biosynthesis efficiency through the kynurenine pathway. Together, NAD3 has been shown in human studies to positively alter molecular markers related to lipid metabolism, cardiometabolic health, and hallmarks of aging through a play-both-offense-and-defense approach to NAD+ optimization. Niacinamide — 200 mg — The amide form of Vitamin B3 (niacin without the flushing), serving as the primary substrate for the NAD+ salvage pathway. The salvage pathway recycles nicotinamide back to NMN and then to NAD+, and niacinamide at 200 mg provides meaningful support for this high-flux recycling pathway in cardiac and vascular tissue, supporting mitochondrial efficiency and cellular energy alongside NAD3's upstream activity. PeptiPump (Bioactive Plant-Derived Peptides, from Nuritas proprietary technology) — PeptiPump represents a breakthrough in peptide-based cardiovascular support. Developed by Nuritas using their AI-driven protein discovery platform that evaluates millions of plant proteins, PeptiPump delivers precision-selected bioactive peptides that support vascular health and endothelial function through mechanisms distinct from and complementary to conventional botanical cardiovascular ingredients. CoQ10 as LEO-HB — Coenzyme Q10 enhanced by LEO-HB (Lipophilic Encapsulation Optimization with High Bioavailability) technology, an eco-friendly solid-solid encapsulation that transforms poorly water-soluble CoQ10 into a free-flowing powder with dramatically improved dispersibility, solubility, and bioavailability. CoQ10 is essential for the mitochondrial electron transport chain in cardiac muscle, which has the highest CoQ10 demand of any tissue in the body. Fucoidan (from Undaria pinnatifida Mekabu Extract, approximately 85% fucoidan) — Fucoidan is a sulfated polysaccharide from brown seaweed with a growing body of research for its role in supporting the glycocalyx, the thin, carbohydrate-rich protective lining of the inner surface of blood vessel walls (endothelium). The glycocalyx is damaged by oxidative stress, inflammation, elevated blood glucose, and age, and its degradation is closely linked to endothelial dysfunction and vascular disease progression. Fucoidan from the mekabu fraction of Undaria pinnatifida, standardized to approximately 85% fucoidan, provides support for glycocalyx regeneration, endothelial lining integrity, and vascular inflammation balance. FitNox (Botanical Nitric Oxide Support Blend) — 250 mg — FitNox is a proprietary blend of botanical ingredients that support nitric oxide (NO) production in the endothelium, the gaseous signaling molecule essential for vascular smooth muscle relaxation, blood pressure regulation, platelet activity inhibition, and vascular elasticity. A 22-day human clinical study demonstrated that 250 mg of FitNox daily supported improvements in blood flow, nitrate and nitrite levels, and exercise-related biomarkers in healthy adults. Nattokinase NSK-SD (from Fermented Soy Bacillus subtilis natto) — NSK-SD is the registered trademark for a standardized nattokinase preparation from Japan BioScience Laboratory. Nattokinase is a serine protease enzyme produced during natto fermentation with well-documented fibrinolytic activity, meaning it directly degrades fibrin, the protein mesh that forms blood clots and thickens blood. Human clinical research on nattokinase demonstrates support for healthy blood viscosity, platelet aggregation, blood pressure, and von Willebrand factor (a cardiovascular risk marker). Contains soy. Citrus Bergamot (from Citrus bergamia, Calabria, Italy) — Bergamot polyphenols from authentic Calabrian bergamot fruit provide cardiovascular lipid and metabolic support through multiple pathways, including AMPK activation (the same metabolic master switch activated by berberine and metformin), HMG-CoA reductase inhibition (the same enzyme targeted by statins through a natural polyphenolic mechanism), and antioxidant protection of LDL against oxidative modification. Contains: Soy (from Nattokinase). Refer to product label for complete other ingredients list and allergen information. Storage Store in a cool, dry place. Keep out of reach of children. Directions Take 3 capsules daily or as directed by your healthcare practitioner. Best taken with or without food as directed. Consult your healthcare practitioner before use, especially if taking blood-thinning medications. Not recommended during pregnancy without practitioner guidance. Healthgevity Cardio NAD+ is a practitioner-trusted advanced cardiovascular and cardiometabolic support supplement available at SOLUDE Wellness & Beauty. It contains NAD3 (Wasabi japonica Extract, Theacrine, Copper-Niacin Complex), Niacinamide 200 mg, PeptiPump (bioactive plant peptides from Nuritas AI platform), CoQ10 (as LEO-HB high-bioavailability technology), Fucoidan (from Undaria pinnatifida mekabu approximately 85% fucoidan), FitNox 250 mg (botanical nitric oxide blend), Nattokinase NSK-SD (from fermented soy), and Citrus Bergamot (from Calabria Italy) per 3-capsule serving. It is designed to support NAD+ status through synthesis and degradation modulation via NAD3, niacinamide NAD+ salvage pathway support, endothelial and glycocalyx function via PeptiPump and Fucoidan, nitric oxide and vascular elasticity via FitNox, healthy fibrinolytic activity blood viscosity and blood pressure via Nattokinase, cardiac mitochondrial energy via LEO-HB CoQ10, healthy cholesterol and triglyceride levels via Citrus Bergamot polyphenols, and balanced inflammatory and oxidative response. Contains soy. Consult practitioner if taking blood thinners. Three capsules daily. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.