HTN 180 Px Extra Strength is designed to optimize cardiovascular function by supporting blood vessel relaxation and coronary blood flow. This formula provides powerful alkaloids such as ajmaline and sparteine that have been investigated for their ability to invoke parasympathetic activity in the brain, potentially helping to calm the mind and body. This Extra Strength formula contains a higher concentration of snake root than our Original HTN 180-Px formula by eight-fold. The inclusion of mistletoe leaf and Hawthorn berry provide vasoactive amines that have been shown in research to support healthy vascular function. Rauwolfia naturally contains a potent alkaloid compound that quickly activates the central nervous system to support normal blood vessel resistance. Its supporting actions on blood vessel relaxation and coronary flow can help optimize cardiovascular function. The resulting clinical benefits explain why HTN 180 Px ES is our top-selling formula. Unlike other rauwolfia products, HTN 180 Px ES does not require toxic solvents such as chlorohexane, phthalates, and toluene to concentrate the alkaloid content. Instead, the plant is harvested when it is at peak potency, avoiding the need for extraction to concentrate the levels. Restorative Formulations uses HPLC MS, an expensive but highly accurate testing method, on both raw materials and finished products to ensure consistency in the levels of this alkaloid from batch to batch. We source Hawthorn leaf and flowers from the South of France because they have the highest levels of naturally occurring vitexin when harvested at just the right time. As a result, we can use the whole herb (leaf and flower), without needing solvents to extract vitexin.* * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.