cFluor^® V610 Anti-Human CD81 (M38)

The mouse monoclonal antibody clone M38 binds to human CD81, a 26 kDa non-glycosylated member of the tetraspanin superfamily (TM4SF). CD81, also known as TAPA-1 (target of an antiproliferative antibody), is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts, and at low levels on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell surface proteins in multimolecular complexes, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8, and CD82 in T cells. PRODUCT DETAILSClone: M38Specificity: CD81Reactivity: HumanFormat: cFluor® V610Isotype: Mouse IgG1, kTested Dilution: 5 µl/TestApplication: Flow CytometryStorage: 2-8°C protected from light. Do not freezeFormulation: Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (BSA Country of Origin USA)Data Sheets: TDS | SDS RECOMMENDED USAGEEach lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. Please briefly centrifuge the reagent vial before use. Use appropriate personal protective equipment per the product safety data sheet when using this product. REFERENCES Fearon D, et al. 1995. Annu. Rev. Immunol. 13:127-149. Wright M, et al. 1994. Immunol. Today 15:588-594. Tubita et al. 2019. Sci. Rep. 1:11117-11128. For research use only. Not intended for use in diagnostic procedures.