Organic Maitake Mushroom Extract | Metabolic Regulation • Hormonal Function

Your immune system, your metabolism, and your hormones don’t operate independently — they’re connected, and when one is under strain the others feel it. Maitake is one of the few mushroom species with clinical evidence across all three. Its signature compound, D-fraction — a beta-glucan unique to Maitake with the highest concentration of any species we offer (>30%) — has been studied for immune activation, blood sugar regulation, and hormonal function, including a clinical trial showing measurable results in women with PCOS. Maitake Benefits: Immune Activation: Maitake’s beta-glucans activate key immune cells — including natural killer cells and macrophages — prompting them to produce the signalling molecules your body uses to coordinate its defences. Studies suggest this leads to a stronger, faster immune response, particularly the branch responsible for identifying and clearing compromised cells. Metabolic Regulation: Research suggests Maitake beta-glucans help the body use insulin more efficiently, supporting steadier blood sugar levels and better energy regulation throughout the day. Animal studies also indicate cholesterol-lowering effects linked to Maitake’s high dietary fibre content (Fukushima et al., 2001). Hormonal Function: In one clinical trial (Chen et al., 2010), Maitake extract induced ovulation in 20 of 26 women with PCOS. Of those, 6 of 8 women who had failed to respond to clomiphene citrate — the standard pharmaceutical treatment — ovulated after switching to Maitake. The mechanism appears to involve improved insulin sensitivity, addressing the metabolic root of PCOS rather than only the hormonal symptoms. Antiviral Support: Maitake’s grifolan beta-glucans appear to mobilise immune responses against specific viral threats, including hepatitis B and HSV-1. Research suggests this works through enhanced natural killer cell activity and broader immune signalling — the same pathways involved in general immune defence, directed at specific targets. Nutritional Density: Maitake is rich in B-complex vitamins, vitamin D, potassium, and dietary fibre, with a high proportion of bioavailable protein. As one of the few medicinal mushrooms that is also a prized culinary species, it has a long track record as a dietary staple in Japan alongside its therapeutic applications. We supply one of the most concentrated Maitake extracts available, clinically dosed and third-party verified for potency. Each capsule serving contains the dry-weight equivalent of 3,600mg of Maitake. The Functional Mushroom Company is committed to unparalleled standards—delivering scientifically substantiated, potent mushroom supplements. Each product is rigorously researched and ethically sourced, embodying our dedication to purity and efficacy for individuals who prioritise integral health and genuine quality