GI Soothing by Standard Process Veterinary is a gut health supplement for dogs and cats with probiotics, postbiotics, and soothing botanicals. Developed with over 50 years of combined clinical veterinary experience, GI Soothing: Calms and soothes the gastrointestinal system Helps manage occasional diarrhea, sensitive stomach, and nervous gut Supports healthy bowel and digestive function Large epidemiologic studies indicate that up to 20–30% of small‑animal veterinary consultations involve GI complaints1 and acute diarrhea affects approximately 8–10% of dogs annually2. GI Soothing supports digestive comfort during times of acute gastrointestinal upset by helping calm the GI tract and encouraging the body’s natural ability to restore balance. By promoting a calmer gut environment, it supports the body’s inherent ability to repair and restore the gastrointestinal lining without persistent irritation. GI Soothing features a biotic blend made of S. boulardii and Lactobacillus fermentate — clinically studied in dogs — to help support a healthy gut environment. Meanwhile, the plant mucilage blend gently coats and soothes the intestinal lining. Biotic Blend of Probiotic Saccharomyces boulardii and Postbiotic Lactobacillus fermentate (90mg per scoop) Probiotic Saccharomyces boulardii supports gastrointestinal health by modulating inflammatory signaling, enhancing gut immune markers, and helping stabilize the gut-brain axis through effects on intestinal barrier function and microbial balance Postbiotic Lactobacillus fermentate (L. fermentum, L. delbrueckii) delivers bioactive fermentation metabolites from lactic acid-producing bacteria, helping modulate innate immune signaling, support stool quality and microbial diversity, and strengthen antioxidant stress‑response pathways without relying on live microbial colonization Mucilage Blend of Marshmallow Root, Slippery Elm Bark, and Okra (240 mg per scoop) Plant‑derived mucilage from marshmallow, slippery elm, and okra provides viscous polysaccharides that swell with water to form a soothing gel, helping create a protective mucosal barrier, support digestion, and promote gastrointestinal comfort during periods of irritation or instability Antibiotics are commonly used to manage acute digestive disturbances in dogs, but research shows they can disrupt gut microbial balance beyond the treatment period, highlighting the importance of supporting gastrointestinal stability and microbial resilience. Frequently Asked Questions Is there a minimum age for GI Soothing? There is no minimum age for GI Soothing. In our field study to date, puppies are responding well to the formula. Can GI Soothing be given with medications? It is recommended to take medication and GI Soothing at least two hours apart. How long should GI Soothing be used? This will be different for each animal. Early field results have shown improvement in stool quality within 7 days. If the animal’s condition worsens, this should be discussed with the prescribing veterinarian. Why does GI Soothing contain yeast? Saccharomyces boulardii is a beneficial yeast that has been studied in dogs and shown to support a healthy intestinal environment and stress-related GI balance. It helps maintain healthy immune signaling in the gut. Nutritional yeast is included for B vitamins and beta-glucans for cellular energy and support. What is spirulina? Spirulina is a nutrient-dense blue-green algae that provides protein, antioxidants, and trace nutrients. In GI Soothing, it helps nourish beneficial microbes and supports a healthy gut environment. What is mucilage? Mucilage is a natural plant gel that when hydrated becomes slippery and coats and soothes mucous membranes, supports GI comfort, can promote healthy bowel function, and provide gentle, whole-food support for digestive irritation. References: O′Neill DG, Church DB, McGreevy PD, Thomson PC, Brodbelt DC. PLoS One. 2014;9(3):e90501. doi:10.1371/journal.pone.0090501 O’Neill DG, Prisk LJ, Brodbelt DC, Church DB, Allerton F. PLoS One. Published online June 11, 2025. Indications for Use: Patients with occasional GI discomfort Patients with occasional diarrhea, sensitive stomach, and nervous gut Patients with increased demands on the enteric and immune systems Directions for Use: Administer orally. For best results, moisten product with water, broth, or wet food. Includes ¼ tsp. scoop. 146 scoops per container. Dose Schedule: Pet Weight Daily Schedule (1 scoop = 1/4 tsp.) 1-15 lbs. ¼ tsp. or 1 scoop 16-35 lbs. ½ tsp. or 2 scoops 36-55 lbs. ¾ tsp. or 3 scoops 56-75 lbs. 1 tsp. or 4 scoops 76-90 lbs. 1 ¼ tsp. or 5 scoops >90 lbs. Add ¼ tsp for every 20 lbs. over 90 lbs. Suggested Use: See dosage schedule. Special Information: One scoop contains more than 1 billion CFU at time of manufacture. Warnings: For animal use only. Keep out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately. Cautions: Safe use in pregnant animals or animals intended for breeding has not been proven. If an animal’s condition worsens or does not improve, stop product administration and consult your veterinarian. Absorption of drugs taken simultaneously may be delayed. Nutrients & Ingredients Amount per ¼ tsp. (670 mg): Biotic Blend 90 mg Yeast (Saccharomyces boulardii), and Lactobacillus fermentate (L. fermentum, L. delbrueckii) Mucilage Blend 240 mg Marshmallow (root), organic slippery elm bark powder, and okra (fruit). Proprietary Blend 300 mg Nutritional yeast, organic SP beet blend (organic Swiss chard juice powder, organic oat flour, organic beet (root), organic beet (leaf) juice powder), organic spirulina powder, and porcine duodenum. Other Ingredients: Lactose. Please consult the actual product label for the most accurate product information. *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.