AF 300

AF 300 is a medication used to treat a wide range of fungal infections. The active ingredient present in this medication is Fluconazole, a triazole antifungal. For effective and safe results, AF 300 should be taken as prescribed by the healthcare provider, even if your symptoms clear up. This medicine can be taken with or without food. Key Features About AF 300 Drug class: Triazole antifungals Chemical class: Fluorobenzenes Product details Active Ingredients Fluconazole Inactive Ingredients Microcrystalline cellulose Magnesium stearate Sodium lauryl sulfate Colloidal silicon dioxide Maize starch Dosage Form Tablet Route of administration Oral Packaging Blister Pack Strength 300 mg Used for Fungal Infections Manufacturer Systopic Laboratories Pvt Ltd Shelf life 24-36 months after the manufacturing date Storage Instructions Store at room temperature away from sunlight and moisture MECHANISM OF ACTION Fluconazole blocks a fungal cytochrome P450-dependent enzyme. This enzyme is required to convert lanosterol to ergosterol, an essential compound of the fungal cell membrane. Due to ergosterol production blockage, the drug causes holes in the fungal cell membranes, increasing permeability which stops the fungus from multiplying or causes it to die. USES Vaginal candidiasis Mucosal and systemic infections Skin and nail infections Systemic fungal infections SIDE EFFECTS Common side effects include headache, nausea, vomiting, diarrhea, stomach pain or abdominal discomfort, altered food taste. Serious side effects include extreme fatigue, loss of appetite, dark urine, peeling skin, rashes, chest tightness, wheezing, etc. INTERACTIONS Severe Interactions Heart rhythm medications: It can cause life-threatening heart rhythm disorders when combined with fluconazole. Other Antifungal/ antibiotics or specialized drugs Major Drug Interactions Anticoagulants Hypertension medications Anti-seizure medications Immunosuppressants Antidepressants Anti-diabetic medications Mild or Moderate Interactions Oral Contraceptives Alcohol PRECAUTIONS AF 300 is generally unsafe during pregnancy as it may cause birth defects or increase the risk of miscarriage. Use with caution if you have liver or kidney disease. Limit or avoid alcohol. Do not self-administer. Avoid the medication if you are allergic to Fluconazole or any other ingredients of the tablet. CONCLUSION AF 300, made by Systopic Laboratories Pvt Ltd, is a triazole antifungal tablet containing fluconazole. Fluconazole can cause serious heart rhythm problems when combined with certain medicines, so tell your doctor about everything you take, including blood thinners, seizure medicines, antidepressants and diabetes drugs. Avoid it in pregnancy, take extra care with liver or kidney disease, and limit alcohol. Take it only as prescribed and finish the full course even if your symptoms clear up. FAQs #sp-ea-24740 .spcollapsing { height: 0; overflow: hidden; transition-property: height;transition-duration: 300ms;}#sp-ea-24740.sp-easy-accordion>.sp-ea-single {margin-bottom: 25px; border: 1px solid #e2e2e2; }#sp-ea-24740.sp-easy-accordion>.sp-ea-single>.ea-header a {color: #0a0a0a;}#sp-ea-24740.sp-easy-accordion>.sp-ea-single>.sp-collapse>.ea-body {background: #ffffff; color: #0a0a0a;}#sp-ea-24740.sp-easy-accordion>.sp-ea-single {background: #ffffff;}#sp-ea-24740.sp-easy-accordion>.sp-ea-single>.ea-header a .ea-expand-icon { float: right; color: #0a0a0a;font-size: 16px;}#sp-ea-24740.sp-easy-accordion>.sp-ea-single>.ea-header a .ea-expand-icon {margin-right: 0;} 1) How does AF 300 work? It blocks an enzyme that the fungus needs to produce ergosterol, a key component of its cell membrane. Without ergosterol the membrane leaks, and the fungus stops multiplying or dies. 2) What if I forget to take a dose? Take it as early as you can recall. If it is almost time for your next dose, skip the missed dose and go on as before. Don’t take a double dose. 3) How should I store AF 300? Store at room temperature. Keep out of reach of children. Keep away from light and moisture. 4) When I’m feeling better, do I stop taking AF 300? Stopping treatment too early can lead to the return of the infection or to resistance to treatment so avoid stopping the treatment early. 5) Can I drink alcohol during the treatment? No. Avoid or limit alcohol as it can worsen the side effects and increase the stress on the liver.