Dopamine receptor D4 (DRD4 or D4DR) antibody

Anti-Dopamine receptor D4 (DRD4 or D4DR) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). There are five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3, and D4 receptors are members of the D2-like family. Dopamine receptor D4 (DRD4) is encoded by the DRD4 gene in human. The D4 receptor is a G-protein coupled receptor that inhibits adenylyl cyclase. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit or hyperactivity disorder, and the personality trait of novelty seeking.