Filter Vials

Filter Vials Sample volume: ~0.4 mL (max fill line) Pore sizes: 0.22 µm / 0.45 µm Membrane options: MCE, PVDF, PTFE, Nylon Material: Medical-grade polypropylene (no leachables) Packaging: 100/pk, 10 pk/carton Designed for fast, leachable-free filtration of small-volume samples directly into an autosampler vial. The syringeless filter vial integrates filtration and sample storage in one device — no syringe, no separate vial, no cap required. Reduces sample loss and preparation time by 70% compared to traditional syringe filtration methods. Applications – Where Filter Vials Excel HPLC / UHPLC Sample Pre-treatment Removes particulates, precipitates, and impurities from liquid samples before injection. Prevents column clogging, extends column life, and improves chromatographic peak shape. Sterile Filtration for Cell Culture & Microbiology Filters cell culture media, buffers, and reagents to ensure sterility. Ideal for microbiological experiments, cell culture, and protein solution preparation. Chemical & Organic Solvent Filtration Compatible with organic solvents, acids, and bases. Choose chemically resistant PTFE membranes for aggressive solvents. Environmental & Food Testing Filters water samples, air sampling extracts, beverages, and liquid food samples to remove particles prior to analysis. Product Structure & Key Features Fast – 2-Step Operation Add sample to outer tube (max 0.4 mL), insert inner tube, and press down. Filtered liquid passes upward through membrane into inner tube. Ready for autosampler. Universal Compatibility Fits autosamplers from Waters, Agilent, Shimadzu, and other major brands. Standard 1.5 mL vial dimensions. High Purity – No Leachables Manufactured from medical-grade polypropylene. Tested with common solvents and LC-MS – no detectable leachables. Cleanroom Production Assembled in a Class 100,000 (ISO 8) cleanroom to minimize particulate contamination. Outer tube: 2 mL capacity, medical-grade polypropylene. Multiple uses possible after rinsing. Inner tube: Push-cap design with pre-slit red silicone rubber / white PTFE sealing septa. Bottom membrane filter (0.22 or 0.45 µm) in various materials. Assembly: Pressing inner tube forces sample through membrane; filtered liquid collects above. Small holes at top release air until locking ring seals. How to Choose the Right Filter Vial Membrane Membrane Hydrophilicity Pore Sizes Best For Chemical Compatibility MCE (Mixed Cellulose Esters) Hydrophilic 0.22, 0.45 µm Aqueous solutions, general laboratory filtration Water, mild buffers Hydrophilic PVDF Hydrophilic 0.22, 0.45 µm Protein solutions, aqueous/organic mixtures Low protein binding, good with mild solvents Hydrophobic PTFE Hydrophobic 0.22, 0.45 µm Organic solvents, air/gas filtration Excellent for aggressive solvents (acetonitrile, methanol, hexane) Hydrophilic PTFE Hydrophilic 0.22, 0.45 µm Both aqueous and organic solutions Universal compatibility, low extractables Nylon Hydrophilic 0.22, 0.45 µm General aqueous and organic samples Good with many solvents, not for strong acids Syringeless Filter Vial vs. Syringe Filter Feature Filter Vial (Syringeless) Syringe Filter + Vial Number of components 1 integrated device (outer tube + inner tube) Syringe, filter, vial, cap – 4 items Sample loss Minimal (direct filtration into final vial) Higher (multiple transfers) Time per sample ~15-20 seconds ~60 seconds or more Cost per filtration Lower (no separate consumables) Higher Best for High-throughput labs, routine HPLC sample prep Larger volumes (>1 mL) or specialized filter materials When to choose Filter Vial: Fast filtration with direct storage, minimal sample loss, reduced consumables. When to choose Syringe Filter: Larger sample volumes (>1 mL) or when you already have an established workflow. Ordering Information – Filter Vials by Membrane & Pore Size Cat. No. Membrane Pore Size Hydrophilicity Septa Packaging 20165001 MCE 0.45 µm Hydrophilic Pre-slit red silicone/PTFE 100/pk, 10 pk/carton 20165002 MCE 0.22 µm Hydrophilic Pre-slit red silicone/PTFE 100/pk, 10 pk/carton 20165003 Hydrophilic PVDF 0.45 µm Hydrophilic Pre-slit red silicone/PTFE 100/pk, 10 pk/carton 20165004 Hydrophilic PVDF 0.22 µm Hydrophilic Pre-slit red silicone/PTFE 100/pk, 10 pk/carton 20165005 Hydrophobic PTFE 0.45 µm Hydrophobic Pre-slit red silicone/PTFE 100/pk, 10 pk/carton 20165006 Hydrophobic PTFE 0.22 µm Hydrophobic Pre-slit red silicone/PTFE 100/pk, 10 pk/carton 20165007 Hydrophilic PTFE 0.45 µm Hydrophilic Pre-slit red silicone/PTFE 100/pk, 10 pk/carton 20165008 Hydrophilic PTFE 0.22 µm Hydrophilic Pre-slit red silicone/PTFE 100/pk, 10 pk/carton 20165009 Nylon 0.45 µm Hydrophilic Pre-slit red silicone/PTFE 100/pk, 10 pk/carton 20165010 Nylon 0.22 µm Hydrophilic Pre-slit red silicone/PTFE 100/pk, 10 pk/carton Frequently Asked Questions Which autosamplers are compatible with these filter vials? Standard 1.5 mL vial dimensions fit Waters, Agilent, Shimadzu, Thermo, PerkinElmer, and most HPLC/UHPLC autosamplers without adapters. What is the maximum sample volume that can be filtered? The outer tube has a fill line at approximately 0.4 mL. Do not exceed this line. After filtration, the inner tube contains about 0.2-0.3 mL of filtered sample – sufficient for most autosampler injections. Can I reuse the filter vial? Designed for single use to avoid cross-contamination. However, the outer tube can be rinsed and reused for the same sample type if needed. Are there any leachables from the polypropylene material? No. The medical-grade polypropylene has been tested with common HPLC solvents and LC-MS – no detectable leachables or extractables. What is the difference between hydrophobic and hydrophilic PTFE? Hydrophobic PTFE repels water and is best for organic solvents. Hydrophilic PTFE wets with water and is suitable for both aqueous and organic samples. Can these filter vials be used for sterile filtration? Yes, 0.22 µm pore size removes bacteria. However, the device is not pre-sterilized; for sterile applications, please request gamma-sterilized versions (custom order). Can I get OEM packaging or custom membrane? Yes. OEM branding, custom membrane materials, and pre-sterilized options are available for volume orders. Contact us for details. Trust & Support – Why Hawach Cleanroom manufactured– Class 100,000 (ISO 8) for low particle background. Leachable-free certified– LC-MS tested with no interfering peaks. Global supply– Stock in regional warehouses for fast delivery. Technical support– Application specialists for membrane selection and troubleshooting. Bulk & OEM options– Custom labeling, private label, and custom membrane combinations. Contact Hawach for a Quotation Enter your email address and our sales staff will contact you as soon as possible. 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