Medicinal Ingredients MSM (Methyl Sulfonyl Methane) 1000 mg Non Medicinal Ingredients Magnesium stearate and hypromellose. Suggested Use Adults: Take 1 capsule 4 times daily with food. Avoid taking at bedtime. CAUTIONS: Keep out of reach of children. Store at room temperature. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Consult a health care practitioner if symptoms worsen. Some people may experience mild gastrointestinal bloating, constipation, or indigestion.