MOTS-C

MOTS-c is a mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA. In laboratory research, it has been studied for its role in mitochondrial-to-nuclear signaling and cellular energy homeostasis. Investigations have focused on its interaction with the AMPK pathway and its influence on glucose and lipid metabolic regulation in controlled research models. Research Characteristics: Mitochondrial-derived peptide studied for retrograde signaling between mitochondria and the nucleus Examined for activation of AMPK-associated metabolic regulatory pathways Investigated in laboratory research for functions in glucose utilization and mitochondrial homeostasis