IMESO Citron Vital Complex Ampoule — Niacinamide & Adenosine 50ml
Most ampoules solve one problem at a time. You find one that calms sensitive skin but skips anti-aging actives. You find one with strong anti-aging peptides but no soothing buffer. After a week, you know exactly which gap you're living with. IMESO Citron Vital Complex Ampoule "A full-spectrum K-beauty ampoule built for skin that needs both calming and visible anti-aging support — at the same time." This 50 ml fluid ampoule from South Korea layers Niacinamide, Adenosine, EGF (rh-Oligopeptide-1), sh-Polypeptide-1, and Sodium DNA into a lightweight, clean-finish texture that absorbs without residue — day or night. Our Licensed Korean Pharmacist & Certified Cosmetic Formulation Manager reviewed this formulation and noted the deliberate structural logic: anti-aging actives and soothing botanicals are formulated together, not as afterthoughts. For skintellectuals who verify every INCI line, and for spa and esthetic professionals sourcing a professional-grade K-beauty ampoule for consistent client results, this is a formula worth reading carefully. Within 10 Minutes The fluid ampoule texture absorbs cleanly — no tacky residue, no heavy film. Skin feels instantly balanced and comfortable. Centella Asiatica and Dipotassium Glycyrrhizate provide immediate visible calming support. Next Morning Skin looks visibly more rested and evenly toned. Sodium Hyaluronate and Beta-Glucan support sustained surface hydration overnight, supporting a visibly plumper, smoother appearance by morning. "A 50 ml ampoule with this many actives — does the formula actually hold together, or does it just read well on the INCI list?" Our pharmacist-certified cosmetic formulation specialist specifically reviewed the layering of this formula. The answer: the Centella Asiatica complex (meristem cell culture, leaf vesicles, and full extract — three distinct forms) functions as the soothing scaffold that makes the higher-activity ingredients — Adenosine, rh-Oligopeptide-1, sh-Polypeptide-1, Sodium DNA — wearable for daily use across skin types. Dipotassium Glycyrrhizate and Allantoin reinforce that soothing layer further. The formula is structured to perform, not just impress on paper. NiacinamideAdenosineEGF (rh-Oligopeptide-1)Sodium DNACentella AsiaticaBeta-GlucanCitrus Junos Extract Results Timeline Period What to Expect Days 1–3 Immediate comfort — the fluid texture absorbs without residue, skin feels balanced. The appearance of visible redness or tightness associated with sensitivity may visibly calm with continued use of the Centella and Glycyrrhizate complex. Week 1 Skin surface looks more hydrated and even-toned. Niacinamide's brightening properties begin to visibly support a more uniform complexion. Sodium Hyaluronate and Beta-Glucan support sustained surface moisture. Week 2 The appearance of fine lines and surface texture may look visibly smoother. Adenosine — a KFDA-recognised anti-wrinkle active — and the peptide complex begin to visibly support a firmer-looking skin surface. Week 4 Cumulative visible improvement in skin tone evenness, surface smoothness, and overall skin comfort. The soothing and anti-aging approaches work in tandem for a visibly more resilient-looking complexion. Individual results may vary. Key Actives — How They Work Niacinamide INCI: Niacinamide KFDA-recognised whitening activeA well-established brightening active with a broad safety profile, suitable for all skin types. Visibly supports a more even-looking skin tone and helps maintain barrier function with continued daily use. Adenosine INCI: Adenosine KFDA-recognised anti-wrinkle activeAdenosine is a KFDA-certified functional anti-wrinkle ingredient, widely used in Korean skincare ampoules. With consistent daily use, it visibly supports a firmer-looking skin surface and may reduce the visible appearance of fine lines over time. EGF — rh-Oligopeptide-1 INCI: rh-Oligopeptide-1 Role: Skin renewal supportA cosmetically used growth factor analog widely incorporated in professional-grade K-beauty ampoules. Visibly supports the appearance of skin renewal and surface texture improvement with consistent use. Popular in esthetic and spa professional protocols. sh-Polypeptide-1 + Sodium DNA INCI: sh-Polypeptide-1 / Sodium DNA Role: Visible firmness + skin resiliencesh-Polypeptide-1 visibly supports a firmer-looking skin appearance with continued use. Sodium DNA supports the appearance of skin resilience and vitality — a premium active increasingly found in high-end K-beauty anti-aging formulations. Triple Centella Asiatica Complex INCI: Centella Asiatica Meristem Cell Culture + Centella Asiatica Leaf Vesicles + Centella Asiatica Extract Role: Soothing + barrier supportThree distinct forms of Centella Asiatica — meristem cell culture, leaf vesicles, and full extract — provide layered soothing and calming properties. This triple-form approach supports skin barrier function and maintains skin comfort throughout a multi-active anti-aging routine. Dipotassium Glycyrrhizate + Allantoin INCI: Dipotassium Glycyrrhizate / Allantoin Role: Calming + skin comfortDipotassium Glycyrrhizate (licorice-derived) and Allantoin are well-established calming ingredients that visibly support skin comfort and a more soothed complexion appearance. Together they reinforce the Centella soothing layer for daily tolerability. Skin Type Compatibility Sensitive / Reactive Triple Centella complex, Dipotassium Glycyrrhizate, and Allantoin provide layered calming and soothing support. Contains fragrance and citrus-derived ingredients — patch test essential for reactive skin types. Mature / Anti-Aging Focus Adenosine (KFDA anti-wrinkle), EGF analog, sh-Polypeptide-1, and Sodium DNA visibly support a firmer, smoother-looking complexion with consistent daily use. Ideal for those layering anti-aging actives in their routine. Combination / Oily Lightweight fluid texture absorbs cleanly with a non-greasy, fresh finish. No heavy emollient base — suitable as a daily ampoule under moisturiser and SPF without contributing to shine or pore congestion. Uneven Tone / Dull Skin Niacinamide and Citrus Junos Seed Extract visibly support a more even-looking, luminous complexion. The antioxidant-rich botanical complex supports the appearance of a brighter skin surface. Professional / Spa Use Multi-active profile — Adenosine, EGF analog, triple Centella, Sodium DNA — makes this a technically robust retail recommendation for esthetic professionals and spa owners sourcing professional-grade K-beauty for client protocols. All Skin Types / Daily Use Formulated for day and night use across all skin types. The balanced soothing-to-active ratio supports consistent daily use without the cumulative irritation risk associated with single-active-dominant ampoules. The Use Case Most Professionals Already Know Apply this ampoule immediately after cleansing — before toner — on evenings when skin has been exposed to environmental stress. The triple Centella complex provides immediate visible calming, while Adenosine and the peptide actives support overnight skin renewal appearance. It is the sequence that esthetic professionals use to stack soothing and anti-aging in a single step, rather than adding a separate calming product. Soothing and anti-aging — not as a compromise, but as a formulation decision. This is professional-grade Korean skincare designed to be read carefully and used daily. Why Our Pharmacist Chose This Licensed Korean Pharmacist & Certified Cosmetic Formulation Manager — Cosmo Gangnam"The structural logic of this ampoule is what makes it noteworthy. Adenosine and Niacinamide are both KFDA-recognised functional actives — anti-wrinkle and whitening respectively — which sets a credible regulatory foundation. The inclusion of rh-Oligopeptide-1, sh-Polypeptide-1, and Sodium DNA in a single ampoule alongside a triple Centella complex is a formulation commitment to visible anti-aging support without compromising daily tolerability. The soothing scaffold is not decorative — it is structurally necessary for this level of active density to remain appropriate for all skin types." Every product on cosmogangnam.com passes our pharmacist's ingredient review before listing. Frequently Asked Questions What does this ampoule do?It visibly supports a more even, smoother, and firmer-looking complexion through a multi-active approach combining brightening (Niacinamide), visible anti-wrinkle support (Adenosine — KFDA-recognised), skin renewal appearance support (EGF analog, sh-Polypeptide-1, Sodium DNA), and a triple Centella Asiatica soothing complex. The lightweight fluid texture absorbs cleanly for day and night use. This product is a cosmetic and is not intended to diagnose, treat, cure, or prevent any skin condition or disease.Who should use this ampoule?Anyone seeking visible anti-aging support alongside daily soothing care — particularly those managing the appearance of fine lines, uneven tone, or visible sensitivity. Well-suited to skintellectual consumers who verify INCI before purchasing, and to esthetic professionals and spa owners sourcing a multi-active K-beauty ampoule for professional retail. Note: this product contains fragrance, citrus-derived, and ginger-derived ingredients — patch test is essential for reactive or sensitive skin types.How do I use it in my routine?Use AM and/or PM. For maximum visible anti-aging benefit, apply directly after cleansing on bare skin before toner. Alternatively, apply after toning as a standard serum/ampoule step. Dispense 3–4 drops, press gently into skin, allow 30–60 seconds to absorb. Layer: Cleanser → This ampoule → Toner (optional) → Moisturiser → SPF 30+ (AM). Always apply broad-spectrum SPF in the morning — this is important when using brightening actives including Niacinamide. Patch test on inner arm, wait 24 hours, discontinue if irritation occurs.Is it safe for sensitive skin?The triple Centella Asiatica complex, Dipotassium Glycyrrhizate, and Allantoin provide substantial calming and soothing support — this ampoule is formulated with daily tolerability in mind. However, it contains fragrance, Limonene, Hexyl Cinnamal, and Linalool (EU-listed fragrance allergens), Citrus Junos Seed Extract (citrus-derived), and Zingiber Officinale (Ginger) Root Extract. Individuals with known sensitivities to any of these should patch test carefully before full-face use. Discontinue and consult a dermatologist if irritation occurs.What makes this different from other K-beauty ampoules?Most ampoules focus on either anti-aging or soothing — rarely both with this level of active density. This formula combines two KFDA-recognised functional actives (Adenosine for anti-wrinkle, Niacinamide for whitening), an EGF analog (rh-Oligopeptide-1), sh-Polypeptide-1, Sodium DNA, and a triple-form Centella Asiatica complex — all reviewed by our pharmacist-certified formulation specialist. The soothing architecture is not cosmetic filler; it is the structural support that makes a high-active ampoule appropriate for daily use across all skin types.How long until I see results?Visible calming and skin comfort support are immediate from the first application. Niacinamide's brightening properties typically become visible within the first week. The appearance of fine lines and surface texture improvements associated with Adenosine and the peptide complex are most apparent at weeks two to four with consistent daily use. Individual results may vary depending on skin type, age, extent of concern, SPF usage, and routine compatibility.How to Use When: AM and/or PM — formulated for day and night use. How much: 3–4 drops per application. Application: Press gently into skin with fingertips on clean, bare skin. Allow 30–60 seconds to absorb fully before layering. Layering (AM): Cleanser → This ampoule → Toner (optional) → Moisturiser → Broad-spectrum SPF 30+. Layering (PM): Cleanser → This ampoule → Toner (optional) → Night cream or sleeping mask. SPF note: Always apply broad-spectrum SPF 30+ in the morning when using brightening actives including Niacinamide. Patch test: Apply to inner arm, wait 24 hours. Discontinue if redness, irritation, or discomfort occurs. Product Details Brand IMESO Product Name IMESO Citron Vital Complex Ampoule Volume 50 ml (1.69 fl. oz.) Product Type Ampoule Texture Lightweight fluid — absorbs cleanly with a fresh, non-greasy finish Usage Time Day & Night Skin Type All skin types Key Actives Niacinamide, Adenosine, rh-Oligopeptide-1 (EGF), sh-Polypeptide-1, Sodium DNA, Triple Centella Asiatica Complex, Beta-Glucan, Citrus Junos Seed Extract Primary Benefit Visibly supports even skin tone, firmer-looking skin, and soothed complexion appearance SPF Note Apply broad-spectrum SPF 30+ every morning when using brightening actives Country of Origin Made in South Korea Regulatory MFDS Compliant. Adenosine: KFDA-recognised anti-wrinkle active. Niacinamide: KFDA-recognised whitening active. Full Ingredients (INCI) Water, Butylene Glycol, Glycerin (humectant), Niacinamide (KFDA-recognised whitening active), Betaine, 1,2-Hexanediol, Trehalose, Coptis Japonica Root Extract, PEG-60 Hydrogenated Castor Oil, Schisandra Chinensis Fruit Extract, Zingiber Officinale (Ginger) Root Extract†, Caprylyl Glycol, Sodium Hyaluronate (humectant), Ethylhexylglycerin, Dipotassium Glycyrrhizate, Citrus Junos Seed Extract, Adenosine (KFDA-recognised anti-wrinkle active), Glyceryl Acrylate/Acrylic Acid Copolymer, Allantoin, Centella Asiatica Meristem Cell Culture, Centella Asiatica Leaf Vesicles, Lactobacillus Extracellular Vesicles, Beta-Glucan (calming humectant), Sodium DNA, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Centella Asiatica Extract, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Chamomilla Recutita (Matricaria) Flower Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, rh-Oligopeptide-1 (EGF analog, skin renewal support), sh-Polypeptide-1, Fragrance‡, Limonene‡, Hexyl Cinnamal‡, Linalool‡ † Ginger (Zingiber Officinale) Root Extract — patch test recommended for those with known ginger sensitivity. ‡ Fragrance, Limonene, Hexyl Cinnamal, and Linalool are EU-listed fragrance allergens. Individuals with known fragrance or citrus sensitivities should patch test carefully before use. Ingredients may vary slightly by batch. Always refer to the physical product label. Free Shipping on Orders $80+ Ships to 57 Countries from South Korea US Duties Covered by Us This product is a cosmetic and is not intended to diagnose, treat, cure, or prevent any skin condition or disease. All descriptions refer to cosmetic appearance only. Individual results may vary based on skin type, age, extent of concern, SPF usage, climate, and routine compatibility. Perform a patch test on a small area before first use. Discontinue use if irritation occurs. Always apply broad-spectrum SPF 30 or higher in the morning when using products containing brightening actives. This product contains fragrance and EU-listed fragrance allergens (Limonene, Hexyl Cinnamal, Linalool), citrus-derived ingredients (Citrus Junos Seed Extract), and ginger-derived ingredients (Zingiber Officinale Root Extract) — patch test recommended for those with known sensitivities. This product does not replace professional dermatological advice or medical treatment.