'Merica Labz Red, White, & Boom

Increased muscle pumps and exercise performance.† Intense focus throughout your workout.† Consistent and sustained energy.† 100% 'Merican!† 3DPUMP Breakthrough® [L-Citrulline (Vegan Fermented) (3000mg), Glycerol, Amla (Phyllanthus emblica) Fruit Extract] 3DPUMP Breakthrough® is a revolutionary new ingredient that is a patented combination of Fermented L-Citrulline, Glycerol (high yield), and a standardized extract of Amla Fruit. This ingredient supports increase vasodilation to the target muscle as well as improved endurance during training by utilizing complimentary pathways of action. If we break down each of these ingredients individually, we can begin to understand what makes this unique combination so beneficial. L-Citrulline - amino acid that converts to arginine and supports nitric oxide production, which aids blood flow and increase muscle pumps. Citrulline has also been shown to enhance exercise performance (particularly in resistance training protocols), boost power, reduce the onset of fatigue, and aid recovery. Glycerol - another common inclusion in pre workout supplements that serves as an osmolyte, which means it encourages muscle cells to attract and absorb more water. This increases cell volumization and cellular swelling, which not only enhances the pump but gives a full look to your muscles. Amla - has a long history of use in Indian medicine as a cardiotonic. It’s high in polyphenols and flavonoids (including pedunculagin, puniglucanin, emblicanin A, and emblicanin B) that are known to possess antioxidant activity and support cardiovascular health. It’s common to find L-Citrulline and Glycerol amongst other nitric oxide and pump inducing ingredients with a track record of efficacy but the real question is if the addition of Amla enhances the experience. Studies have shown that this answer is undoubtedly yes! One study measured cell volumization and muscle swelling because of performing lower body exercises using multiple interventions, which included placebo, 1500mg glycerol, 150mg Amla, and 1350mg glycerol + 150mg Amla. The results showed that all interventions, including placebo, produced positive results on leg size and lean body mass, however, the glycerol + Amla produced significantly better results than the other interventions. The glycerol + Amla group increased their thigh circumference by 2.21 cm on average and had an increase of 693.1 grams in total body mass. These results make the combination of adding Amla to the already classic benefits of L-Citrulline and Glycerol extremely promising when it comes to making positive improves in your goals when it comes to sport performance products. Creatine Monohydrate Sometimes called the “grandfather” of dietary supplements, creatine is, along with caffeine, one of the most extensively studied dietary compounds. Certainly, it is the most well-studied ergogenic aid. Generally speaking, the extensive amount of data on creatine demonstrates that it positively contributes to dilation of the vasculature, plasma-nutrient mobilization, post-workout nitrogen retention and protein synthesis, along with dose-dependently increasing contractile force through ATP (adenosine triphosphate) provision (i.e., it helps support increased strength). If the human body could be considered a bank account, then ATP would be the currency, and every cellular process would be like spending a little money from that account. Without making a deposit, the account runs dry (fatigue). Unfortunately, making a direct deposit to that account in the form of exogenous adenosine triphosphate is impossible, given that ATP itself is incredibly unstable. The use of supplemental creatine, however, is analogous to making a deposit in the body’s energy bank, given that creatine is eventually metabolized to ATP via several steps. In skeletal muscle, creatine is first phosphorylated into its primary derivative, known as phosphocreatine (PCr), by the muscle-specific creatine kinase, creatine kinase-MB (muscle-brain). Following the phosphorylation of creatine, phosphocreatine may then anaerobically donate a phosphate molecule to adenosine diphosphate (ADP) to form the ATP required during the initial stages of intense muscular contraction. The result is not only an increase in contractile force, but also an increase in potential type IIx (‘fast-twitch’) muscle recruitment – the type of muscle fibers which are not only traditionally associated with speed, strength, and impressive physiques, but which are also unsurprisingly the most energy-demanding fiber types. Literally speaking, creatine contributes to the building of muscle. Both through the ATP provision just described, as well as effects on nutrient mobilization, protein-sparing, and fluid dynamics, creatine has been consistently demonstrated to increase both lean mass and muscle mass in clinical data. In the short-term, these effects are most likely the result of extra-cellular fluid retention normally associated with exogenous creatine use. In the long term, these effects are likely attributable to creatine’s collective effect on muscle metabolism. The most recent research on creatine suggests it exerts direct effects on muscle metabolism, including altering the expression of genes responsible for ribosomal assembly, attenuating the breakdown of leucine, and most famously, by expanding cell volume. Cutting through the jargon, let us just say that the amount of creatine monohydrate contained in Red, White, and Boom simply works: these servings have been shown time and again to significantly increase lean body mass and muscle volume, lower fatigue, and improve performance (measured in several ways). Beta Alanine Carnosine is a bit of an odd duck: we know that it is crucial for muscle function, and that dietary sources of caronsine are essential, but we don’t know precisely how it’s working. Moreover, for decades, we had no idea how to increase intramuscular concentrations, as exogenous carnosine sources degraded in the body so fast as to be effectively useless. Enter beta-alanine. Simply a different iteration of one of the amino acids that comprises carnosine itself (alanine), beta-alanine has proven to be the most effective means of significantly increasing intramuscular concentrations of carnosine – and therefore of promoting all of carnosine’s various beneficial effects on muscle performance. If that weren’t enough, beta-alanine has also demonstrated beneficial physiological effects independent of its parent compound. In order to understand why, though, we need to first understand some of the basics behind carnosine itself. Carnosine, a cytoplasmic dipeptide synthesized from the precursors L-histidine and l-alanine, is present in high concentrations in skeletal muscle and plays a pivotal role as a, “chemical buffer” in myocytes (muscle cells). It has long been known that carnosine concentrations are highest in glycolytic, rather than oxidative muscle fibers (roughly speaking, explosive vs., endurance muscle fibers, respectively), and thus long hypothesized that this amino acid is required for sustained performance during supramaximal exercise. Recent research demonstrates that carnosine exerts its physiological effects in long hypoxic (low oxygen) drives by functioning as a high-capacity pH buffer in skeletal muscle, preventing the pH ratio of plasma from dropping too low – and therefore preventing crucial pH-dependent processes such as protein synthesis from being inhibited by acidosis. Despite its critical role in skeletal muscle anaerobic performance, intramyocellular synthesis of carnosine is rate-limited by the availability of l-alanine. Unfortunately, the majority of literature demonstrates that attempting to increase intramuscular levels of carnosine via either direct carnosine or alanine supplementation is largely ineffective due to carnosine/alanine pharmacokinetics. Enter beta-alanine. Research with beta-alanine demonstrates consistent and dose-dependent increases to intramuscular carnosine concentrations with beta-alanine supplementation, with certain studies showing an increase of 40-60% with chronic administration. These same literature reveal a synergistic effect of exercise on beta-alanine supplementation, whereby the muscle adaptive changes associated with resistance training promote further intramuscular carnosine production in response to beta-alanine supplementation. In simpler language, this essentially means that beta-alanine is a dietary supplement that promotes its own effects in combination with exercise. As you exercise, you simultaneously intensify beta-alanine’s physiological actions – both directly, as well as in the production of intramuscular carnosine. Once ingested, beta-alanine’s exercise-specific beneficial activity is well-established. Elevation of intramuscular caronsine content via beta-alanine supplementation has been shown to improve performance in the following ways. Both acute and chronic increases in total work capacity, measured by total volume during exercise sessions. Highly significant increases to TTE (total time to exhaustion), one of the most accurate and comprehensive measures of endurance. In various trials, beta-alanine supplementation has been shown to increase TTE by upwards of 20%. Increases to total muscle power output in both acute and chronic trials, suggesting that beta-alanine’s most significant benefit is to those engaging in power-dependent resistance training. In total, a significant body of research exists to suggest that beta-alanine may significantly increase muscle power output, strength, training volume and output, overall performance in hypoxic (oxygen-deprived) conditions and peak VO2 max (oxygen holding capacity). These myriad benefits make beta-alanine both one of the most-studied, and most well-rounded dietary supplements. Beta-alanine not only has direct, actionable physiological effects, but also promotes critical muscle physiologic adaptations that promote its own effects. Arginine Nitrate (as NO3-T®) Nitric oxide (NO) is involved in many vascular and cellular functions as a signaling molecule for cellular respiration, vasodilation, and angiogenesis. NO is produced through both endogenous and exogenous pathways through dietary nitrate ingestion. Nitrates are converted to nitrite, which is then converted to nitric oxide. Found naturally in many foods such as leafy greens and beets, NO has a long history of scientific literature to back its potential effects as an ergogenic aid and other health-promoting effects. In terms of athletic performance, NO typically will make an impact through a few different mechanisms, such as: Delayed onset of fatigue Increased nutrient and oxygen delivery to working muscles via increased vasodilation Increased loss of metabolic by-products because of high intense exercise However, when it comes to exercise and utilizing NO for its benefits in athletic performance, consuming whole foods is not always the most optimal form, so dietary supplemental forms of nitrates are often used to help provide this benefit. Content continues unchanged through the remainder of the document. † These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnore, treat, cure, or prevent any diseases.