COL3A1 Recombinant Rabbit mAb (S-4338)

Product Specification Host Rabbit Antigen Collagen III Synonyms Collagen alpha-1(III) chain; COL3A1 Location Secreted Accession P02461 Clone Number S-4338 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC-P, ICC Reactivity Hu Positive Sample RD Purification Protein A Concentration 0.5 mg/ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 Stability & Storage 12 months from date of receipt / reconstitution, -20 °C as supplied Dilution application dilution species WB 1:500-1:1000 Hu IHC-P 1:250 Hu ICC 1:500 Hu BackgroundCollagen III is a homotrimeric fibrillar protein composed of three identical α1(III) chains wound into a triple helix, encoded by the COL3A1 gene, that copolymerizes with collagen I to endow skin, blood vessels and hollow organs with extensibility and compliance, and whose mutations or deficiency cause the life-threatening vascular fragility syndrome Ehlers–Danlos syndrome type IV.