Rejuran S 1x1ml

Rejuran S 1 x 1 ml – salmon-derived polynucleotide injectable for acne and atrophic scars Rejuran S is the scar-directed variant of PharmaResearch’s Rejuran range: an injectable polynucleotide gel for acne scars, other atrophic scars and defined areas of uneven skin texture. It is a skin booster, not a filler: no cross-linked hyaluronic acid, no calcium hydroxylapatite, no poly-L-lactic acid. Its higher viscosity supports targeted placement in defined treatment areas rather than broad-field coverage. Choose it when the target is a scar or a limited patch of uneven texture. Not for volume, and not for broad-field treatment – that is the 2 ml Rejuvenation with PN. Product overview What it does Supports dermal matrix remodelling in a defined area. Does not replace volume. Clinical positioning Tissue restoration and reconstruction; acne and atrophic scars; skin of the face, neck, décolleté and hands Depth Intradermal, per the IFU Onset 2 to 4 weeks, per the manufacturer Course Three sessions about a month apart, per the manufacturer Who it suits A scar or a texturally uneven area of limited size Specification Product type Sterile injectable polynucleotide gel, prefilled syringe Manufacturer PharmaResearch Co., Ltd., Gangneung, South Korea Regulatory status CE-marked Class III medical device Active substance Sodium polynucleotide (PN), long-chain, DOT process Material origin Wild chum salmon DNA, Oncorhynchus keta Presentation 1 ml prefilled syringe Storage 1 to 30 °C, away from sunlight. No cold chain Intended users Healthcare professionals qualified under national law How it works Polynucleotides are DNA chains purified from salmon. In the dermis they form a hydrophilic, scaffold-like matrix and are associated in the literature with fibroblast activity, extracellular-matrix remodelling and tissue-repair pathways. Enzymes break the chains down over the following weeks. The mechanism is described in published reviews as proposed rather than fully established. The polynucleotide chain is degraded. What the fibroblast does in response is what remains. Treatment areas Face Intradermal, into and under the scar or the area of uneven texture Neck, décolleté, hands Intradermal, per the IFU Volume per point and per session follows the IFU. Safety profile Expect erythema, oedema and bruising at the injection sites, plus the raised papules the technique produces on purpose; they settle over the following days. As with any injectable, treatment requires appropriate anatomical knowledge and injection technique. Published polynucleotide literature to date has not identified vascular occlusion as a reported complication, although the available safety dataset remains limited. Contraindications Known hypersensitivity to any component Active infection, inflammation or skin lesion at the injection site Anything the IFU excludes The IFU in the carton carries the full list and takes precedence over this one. Choosing within the Rejuran range Rejuran Rejuvenation with PN comes as 2 ml and covers a broad field. Rejuran I is the 1 ml version for the eye area, formulated thinner so papules settle faster in eyelid skin. Rejuran HB plus adds hyaluronic acid and lidocaine. Rejuran S is the 1 ml version for a scar or a small area. On scars, the evidence is worth knowing before you quote it to a patient: a randomised controlled trial covers polynucleotide injection for post-surgical scar prevention, and a case series covers facial and post-traumatic scars. A prospective randomised study against placebo exists for atrophic acne scars, but used a polynucleotide from a different source. None used this syringe. Other polynucleotides in the catalogue Salmon-derived polynucleotides are one branch of the class. The closest neighbour by indication is Mastelli’s trout-derived Plinest One, positioned for atrophic scars and stretch marks including body areas; Plinest is the general face, neck and décolleté product of that line. The lines differ in source species, purification technology and the volume of published data. Everything in the class sits under biostimulators. FAQ What does the S stand for? Practitioners read it as scar, and that is how the variant is positioned on the market. PharmaResearch does not explain the letter in its own product information, and the registered indication is broader than scarring. Is Rejuran S a dermal filler? No. It is a polynucleotide injectable. It is not formulated for volume augmentation or contour correction, and it contains no cross-linked hyaluronic acid. How does it differ from Rejuran Rejuvenation with PN? Rejuvenation with PN is the 2 ml syringe for broad-field treatment of the face, neck, décolleté and hands. Rejuran S is the 1 ml syringe for a scar or a defined area of uneven skin. How is it stored? At room temperature, between 1 and 30 degrees Celsius, protected from direct sunlight. No cold chain is required. {“@context”:”https://schema.org”,”@type”:”FAQPage”,”mainEntity”:[ {“@type”:”Question”,”name”:”What does the S stand for?”,”acceptedAnswer”:{“@type”:”Answer”,”text”:”Practitioners read it as scar, and that is how the variant is positioned on the market. 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