Advocate Ultra Chew for Large Dogs 11.1 - 22 kg provides all-in-one monthly protection against ticks, fleas, demodex mites, heartworm disease and intestinal worms, including tapeworms. Advocate Ultra Chew is the fastest-acting all-in-one against fleas and ticks, providing rapid protection from fleas, paralysis ticks, brown dog ticks and bush ticks. It also effectively treats and controls generalised demodectic mange caused by demodex mites. Advocate Ultra Chew prevents heartworm disease. It treats and controls intestinal worms, including adult and juvenile roundworms and hookworms, plus major tapeworms, including hydatid and flea tapeworms. As some of these intestinal worms are zoonotic and can affect human health, Advocate Ultra Chew helps protect both your pet and your family. Feeding Guide: Administer Advocate Ultra Chew orally once a month, preferably on the same date, with or following food. This palatable chew is typically accepted by hand; if not, it may be hidden in food. Refer to the product leaflet for full instructions. Ingredients: Each chew contains 450 mg LOTILANER, 114 mg PYRANTEL (as embonate), 114 mg PRAZIQUANTEL, 0.45 mg MOXIDECTIN