Calming Comfort Pro is a calming supplement for dogs and cats designed to promote relaxation and nervous system health using whole food-based ingredients. Beneficial for pets in stressful situations like thunderstorms, fireworks, travel, and separation Aids in calming dogs and cats Promotes normal behavior May help manage stress-related behaviors in dogs and cats Relief from occasional anxiousness Supports neurotransmitter synthesis for behavioral health Promotes a positive mood Helps control cortisol response in dogs Promotes normal sleeping habits in cats Additional Product Attributes Contains a blend of amino acids that interact with calming neurotransmitter pathways Contains L-theanine — clinically studied in dogs and cats to promote calm behavior Contains L-theanine, L-tryptophan, and GABA — clinically studied in dogs to promote calm behavior Encourage Confidence & Composure with a unique combination of ingredients Recent studies have shown that 72.5% of dogs express anxiety-like behaviors,1 and 66.7% of cats were prone to anxiety or fear.2 In addition, stimuli such as car rides/travel, thunderstorms, veterinary visits, and fireworks have the potential to induce stress-induced behaviors in both dogs and cats.3-6 Help pets and pet parents enjoy calmer days and happier nights with Calming Comfort Pro from Standard Process Veterinary Formulas™. It’s made with a unique combination of research-supported ingredients that can help your patients cope with the mental stimulation of loud noises, unfamiliar settings, and everyday life. Calming Comfort Pro is Made with Research-Supported Ingredients L- theanine (70 mg/serving) Promotes a healthy stress response through supporting natural glutamate-GABA signaling pathways7,8 Magnesium (14 mg/serving) Magnesium status is associated with stress response9 L- tryptophan (70 mg/serving) Building block for serotonin10 γ-aminobutyric acid (GABA) (50 mg/serving) Supports calming nervous system signaling pathways in the brain and spinal cord7,8,11-13 Frequently Asked Questions Can I give Calming Comfort Pro to my dog or cat with other medications? As it is designed to be used, the ingredients in Calming Comfort Pro have no known contraindications or interactions with any drug. It is always best to consult your veterinary professional when considering the addition of a supplement to your pets’ healthcare plan. Find a full list of available Standard Process suppliers here. Is the product palatable? When tested in our in-home trial, pet parents reported acceptance 86% of the time. The liver powder in the product aids in palatability and has been well accepted. How long does a bottle last? The length of time a bottle will last is based on the animal’s weight. There are 172 - 1/4 tsp servings in the bottle. A 1/4 tsp scoop is included in the bottle along with administration instructions by weight on the bottle label. Is this product appropriate for pets with noise sensitivities? Yes. The ingredients in Calming Comfort Pro work synergistically to provide comforting and calming support to cats and dogs including those with noise sensitivities. What makes this product different from others on the market? Calming Comfort Pro was formulated by the nutrition scientists at our Nutrition Innovation Center. Adhering to our philosophy of providing nutrients as nature intended, Calming Comfort Pro is a whole food-based option for a multimodal approach to supporting animals experiencing fear, stress, and anxiousness. How long does this calming supplement take to work? This supplement supports relaxation and works best when given daily for at least 30 days. Some pets may show results sooner, but consistency is key. Regular use will also help cats and dogs stay calmer during stressful situations. References 1. Salonen, M., et al. Scientific Reports 10, 2962 (2020). 2. Grigg, E.K., Kogan, L.R., van Haaften, K. & Kolus, C. Journal of Feline Medicine and Surgery 21, 902-909 (2019). 3. Shin YJ, S.N. J Vet Sci. 17(2):153. doi:10.4142/jvs.2016.17.2.153(2016). 4. Franzini de Souza CC, M.C., Dias DPM, Almeida NA dos S, Medeiros MA de. Physiol Behav. 169:208-215. doi:10.1016/j.physbeh.2016.12.006(2017). 5. Stella J, C.C., Buffington T. Appl Anim Behav Sci. 143(2-4):157-163. doi:10.1016/j.applanim.2012.10.014(2013). 6. de Souza Machado D, O.P., Machado JC, Ceballos MC, Sant’Anna AC. PLoS One. 15(4):e0230999. doi:10.1371/journal.pone.0230999(2020). 7. Jewett BE, S.S. Physiology, GABA. StatPearls. 8. Pike AL, H.D., Lobprise H. Journal of Veterinary Behavior. 10(4):324-331. doi:10.1016/j.jveb.2015.04.001(2015). 9. National Research Council. The National Academies Press (2006). 10. Jenkins TA, N.J., Polglaze KE, Bertrand PP. Nutrients. 8(1). doi:10.3390/nu8010056(2016). 11. Herbel J, A.J., Gautier C, Melchert M, Aurich C. Animals 2020;10(11):2114. doi:10.3390/ani10112114(2020). 12. Franzini de Souza, C.C., Maccariello, C. E., Dias, D. P., Almeida, N. A., & Medeiros, M. A. Physiology & behavior 169, 208–215(2017). 13. Shin, Y.J., & Shin, N. S. Journal of veterinary science 17(2), 153–158(2016). Indications for Use Beneficial for animals in stressful situations like thunderstorms, fireworks, travel, and separation Patients who exhibit stress-related behaviors Support for calming in animals easily influenced by common stimuli Directions for Use: Administer orally. Best if given with food. Pet Weight Daily Schedule Dogs 5-15 lbs. ¼ tsp. = 1 scoop Dogs 16-35 lbs. ½ tsp. = 2 scoops Dogs 36-50 lbs. ¾ tsp. = 3 scoops Dogs 51-70 lbs. 1 tsp. = 4 scoops Dogs 71-90 lbs. 1 ¼ tsp. = 5 scoops Dogs >90 lbs. 1 ½ tsp. = 6 scoops Dogs and Cats <5 lbs. Consult with veterinarian Cats 5-20 lbs. ¼ tsp. = 1 scoop Includes 1/4 tsp scoop. Suggested Use: Stated amounts depend on dose. Warnings: For animal use only. Keep out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately. Caution: Safe use in pregnant animals or animals intended for breeding has not been proven. If animal’s condition worsens or does not improve, stop product administration and consult your veterinarian. Nutrients & Ingredients Amount per ¼ tsp. (580 mg): L-Theanine (Suntheanine®) 70 mg, L-Tryptophan 70 mg, Gamma-Aminobutyric Acid (GABA) 50 mg, Magnesium (Mg Hydroxide) 14 mg Proprietary Blend 230 mg Bovine liver, ashwagandha root, bovine colostrum, organic buckwheat (aerial parts) juice powder, bovine thymus PMG™ extract, bovine thymus Cytosol™ extract, and organic kidney bean (aerial parts) juice powder. Suntheanine® is a registered trademark of Taiyo International, Inc. Please consult the actual product label for the most accurate product information. *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.