This men’s multivitamin is focused on the anatomy and nutrient needs of men, geared toward helping them have and maintain proper nutrition. Aiding in mental alertness and increased energy. Contains a complete blend of the essential vitamins and minerals, powerful fruit and berry antioxidants to support detoxing, natural energizers from herbs and berries for a natural energy lift with no caffeine.* Formula Purposes & Benefits Men’s Multivitamin is formulated to support cardiovascular health, hormonal health, metabolic health, immune health, digestive health, sexual function, cognitive function, positive mood, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high-quality ingredients. Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient Vitamin A (beta carotene) Supports vision health, skin health, immune health, and increases antioxidant support (182, 183). Supports antioxidant function via decreased inflammatory cytokines (inflammation), decreased reactive oxygen species, and increased L-glutathione production (master antioxidant) (182, 183). Supports visual health via increased amounts of plasma vitamin A in macular (eye) tissues (182,183). Vitamin C Supports immune, cardiovascular, skin, cognitive, fat burning, and digestive health (97, 98). Supports immune health via increased oxidant, free radical scavenging, and fueling neutrophilic (immune cell) activity in chemotaxis, phagocytosis, and microbial killing (97,98). Supports fat burning by increasing carnitine biosynthesis (molecule required for mitochondrial fatty acid oxidation) (97,98). Supports accelerate bone healing after a fracture, increase type I collagen synthesis, and reduce oxidative stress (inflammation) (98). Calcium Carbonate Supports bone health, muscle function, and cardiovascular health (36,37). Regulates processes of bone resorption, mineralization, and fracture repair (36,37). Increases the effect of physical exercise on bone mineral acquisition in the period preceding puberty (36,37). Prevents the development of preeclampsia (36,37). Vitamin D Supports exercise performance, immune health, muscle growth, optimal bone health, hormonal health, immune function, increased sexual health, cardiovascular health, glucose tolerance, strength, and positive mood (77,78,79). Supports hormonal health via high amounts of vitamin D receptor (VDR) activity in hormone based negative feedback loop reactions (77,78). Supports cardiovascular health via improved absorption of calcium, reduced atherosclerotic activity, stimulating cardiomyocytes, and improved vascular health (77,78). Supports exercise performance via reduced exercise associated inflammation and muscle damage (77,78). Supports sexual health via increased activity of Vitamin D receptor activity of testosterone production (79). Supports immune function via decreases of inflammatory cytokines and aiding immune cells (77,78). Supports joint health via regulating calcium and phosphorus and bone remodeling along with other calcium-regulating actions (77,78). Vitamin E Supports immune function, cognitive health, cardiovascular health, and bone health (204,205,206,207,208) Supports immune health via neutralizing free radicals and reactive oxygen species, and increased T lymphocyte-mediated immune function (204). Supports cardiovascular health via reduced cholesterol (204). Supports cognitive function via reduced oxidative stress, inflammation, and DNA damage of neuronal tissues (208). Vitamin B1 (Thiamine) Supports aerobic energy metabolism (oxidative phosphorylation), cell growth, optimal neuronal conduction (nerve impulses), and cardiovascular health (94). Supports cardiovascular function and aids as a neuroprotective agent in individuals with vitamin B-1 deficiencies (94, 95). Vitamin B2 (Riboflavin) Supports conversion and activation of other B vitamins, red blood cell production and serves as a cofactor for both glucose and fat metabolism (energy production) (92,93). Vitamin B3 (Niacin) Major B vitamin that supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very-low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9). Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9). Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9). Supports healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9). Prevents pathologies(diseases) such as Pellagra and reduces the prevalence of nervous anorexia, cancer, and Crohn’s disease (10, 11). Vitamin B6 Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). May support blood sugar regulation in women with gestational diabetes (40). Cofactor for enzymes involved in DNA metabolism (40). Vitamin B12 Supports proper DNA synthesis, folate cycle function, energy production, cognitive function, and immune health (51,53). Aids as an antioxidant via direct scavenging of reactive oxygen species (inflammation), preserving l-glutathione levels (master antioxidant), and reducing oxidative stress (51). May prevent vitamin b-12 deficiency diseases such as anemia, neurodegenerative disease, cardiovascular disease, and osteoporosis (53). Zinc Supports immune function, skin health, cognitive function, and vision (172,173). Supports stimulation of the innate and adaptive immune system (172,173). Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173). Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173). Biotin Supports conversion of food into cellular energy, hair health, skin health, and cognitive function (213,214). Enhances glucose breakdown into skeletal muscle tissue (213,214). Vitamin B5 Supports energy production, cell growth, cell repair, cognitive function, increased hippocampal volume (memory), and optimized bioenergetics (burning of carbohydrates, fat, and protein) (96). Magnesium Supports optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91). Supports biological reactions such as ATP-fueled reactions and pancreatic insulin secretion (90,91). Supports reduction systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91). Reduces peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91). Copper Supports healthy blood sugar levels, energy metabolism and cholesterol management (143,144). Selenium Supports antioxidant function, cardiovascular health, cognitive function, thyroid health, and immune health (145, 146). Combats atherosclerosis, high cholesterol (hypercholesterolemia), and type 1 diabetes (147). Supports thyroid health via decreased circulating thyroid autoantibodies in patients with chronic autoimmune thyroiditis (AIT) (146). Increases the activity of selenoproteins that decrease reactive oxygen species (inflammation), increases natural killer activity, and increases glutathione (master antioxidant) levels (145,147). Manganese Supports enzymatic antioxidant reactions, increased bone mineral density, and blood sugar regulation (148,149). Molybdenum Increases enzymatic reactions involved in sulfite metabolism and detoxification (150). Chromium Supports insulin function, reduced cholesterol, improved blood sugar regulation, and may lower cholesterol (218,219). Lutein A carotenoid that supports vision health, immune health, cardiovascular health, and combats diabetic retinopathy (155,156). Supports increased lutein concentration in the macula and exhibits various features such as anti-inflammatory, anti-oxidative, and blue light-filtering effects (155,156). Supports visual health via increased lutein concentration in the macular layer of the retina, reduced susceptibility to age-related macular disease, reduced prevalence of cataracts, and improved plasma level of lutein and retinal macular pigment level (155,156). Lycopene Supports prostate health, cardiovascular support, antioxidant, anti-inflammatory, and chemoprotective properties against cancer (191,192, 193). Combats inflammation via scavenging of free radicals and reduces oxidative damage of DNA. (191,192,193). Combats carcinogenesis via carcinogen-metabolizing enzymes, apoptosis (cancer cell death), anti-proliferation, pro-differentiation, and anti-lipid peroxidation activities. (193). Inhibits phosphorylation of anti-oncogenes such as p53 and Rb. It also inhibits G0/G1 and S-phase of the cell cycle (193). Spirulina Supports reduced cholesterol, blood pressure, blood sugar regulation, reduces inflammation, reduced body fat, and supports antioxidant function (301, 302). Goldenseal Root Supports digestive health, antibacterial activity, and antioxidant support (201, 202). Supports antioxidant function via levels of berberine (alkaloid) (201,202). Echinacea Increases antiviral, anti-microbial, antioxidant capacity, and supports a strong immune system (159,160). Supports immune health via decreased impro-inflammatory markers (cytokines IL-6, IL-8, and TNF) (159,160). Supports adaptive and innate immunity via increased monocytes, neutrophils, natural killer cells, and CD8 T cells (159,160). Garlic Supports cardiovascular health, immune health, joint health, reduced inflammation, gut health, and enhanced antibacterial activity (161). Supports cardiovascular health via reduced hypertension, reduced total cholesterol, reduced arterial stiffness (hardening of arteries), and markers of atherosclerosis (161). Supports joint health via reduced NF-κB activation (inflammation) in human fibroblasts cells and reduced prevalence of pain in individuals with rheumatoid arthritis (162). Supports gut health via increased prebiotic properties, increased microbiome population, and increased Lactobacillus and Clostridia species (163). Supports immune health via a reduction in inflammatory markers (CRP, TNF, IL-6) (164). Green Tea Extract A potent polyphenolic antioxidant that supports blood pressure, insulin sensitivity, and metabolic health (25). High in ECGC (epigallocatechin gallate) (25). ECGC is shown to reduce body fat mass, increase fat oxidation(burning) and increase caloric expenditure during exercise. (25). Potent anti-inflammatory compound supporting glutathione production and inhibition of pro-inflammatory markers (cytokines). (26). Reduces oxidative stress (chronic inflammation in the body) (26). Hawthorn Berries Supports cardiovascular health and combats metabolic syndrome (165). Supports cardiovascular health via reduced atherosclerotic lesion areas, reduced cholesterol synthesis (acyl-coA-cholesterol acyltransferase enzyme), reduced very-low-density lipoproteins (VLDL), and inhibited platelet aggregation (165). Cinnamon Bark Extract Supports blood sugar regulation and cardiovascular health (166). Decreases levels of fasting plasma glucose, total cholesterol, LDL-C, triglyceride levels, and an increase in HDL-C levels (166). Supports blood sugar regulation by improving insulin sensitivity and enhanced glucose uptake (166). Bilberry Fruit Extract Supports vision health, cardiovascular function, increased nitric oxide production, blood sugar regulation, and antioxidant support (167,168). Grape Seed Extract Supports increased nitric oxide production, reduces blood pressure, reduces DNA damage, increases collagen production, increases bone strength, and aids as a neuroprotective agent (31). Supports antioxidant function via modulation of antioxidant enzyme expression, protection against oxidative damage, and reduced reactive oxygen species (31). Supports cardiovascular health via reduced atherosclerosis, inhibiting lipid peroxidation, and improved endothelial vascular function (31). Black Currant Supports immune function via high levels of polyphenols and reduction of inflammation (169). Supports cardiovascular health via reductions in LDL Cholesterol (169). Pomegranate Extract Supports reduced blood pressure, increased nitric oxide production, immune health, blood sugar regulation, prostate health, gut health and aids as an antimicrobial compound (170). Supports prostate health via high polyphenolic antioxidant levels (three times the antioxidant activity of green tea) that protect the prostate gland from inflammation (170). Supports reduced blood pressure via increased nitric oxide production, increased cardiac output (blood flow), and reduced cholesterol levels (170. Supports digestive health via combating inflammatory bowel disease (171). Supports immune health via reduced inflammatory cytokines (markers of inflammation) throughout the body (171). Proper Use of This Supplement Suggested Use: As a dietary supplement take two (2) veggie capsules once a day. For best results, light exercise and a sensible diet are recommended. Use this product for no less than 8 weeks for maximum results. Do not exceed 4 capsules a day. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. High-quality vitamins, minerals, herbs and nootropics in an effective and efficaciously dosed formula. 2. Uses cheap sources of vitamins, minerals, herbs, and nootropics that contain high amounts of fillers and heavy metals. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.