Deriva-BPO Gel 20gm — Product Description Overview Deriva-BPO Gel is a topical combination medication manufactured by Glenmark Pharmaceuticals Ltd, used in the treatment of acne vulgaris. Supplied in a 20 gm tube, it combines two well-established acne-fighting ingredients — adapalene and benzoyl peroxide — into a single once-daily formula that targets both the formation of new blemishes and the bacteria behind existing breakouts. Deriva-BPO Gel is generally suitable for adults and adolescents aged 9 years and older and is commonly prescribed for mild to moderate acne affecting the face, chest, or back. What Deriva-BPO Gel Contains Adapalene 0.1% w/w — a synthetic third-generation retinoid Benzoyl Peroxide 2.5% w/w — an antimicrobial and keratolytic agent Form: Topical gel Pack size: 20 gm tube Manufacturer: Glenmark Pharmaceuticals Ltd Availability: Prescription-only medication What Deriva-BPO Gel Is Used For Deriva-BPO Gel is indicated for the treatment of acne vulgaris, particularly cases involving a mix of comedonal acne (blackheads and whiteheads) and inflammatory acne (red, swollen pimples). It's commonly recommended for patients whose acne doesn't respond adequately to single-ingredient treatments, since the combination addresses multiple contributing factors at once. Deriva-BPO Gel helps to: Reduce the formation of new blackheads and whiteheads Clear existing pimples and inflamed lesions Control excess oil (sebum) production Reduce populations of acne-causing bacteria (Cutibacterium acnes, formerly Propionibacterium acnes) Improve overall skin texture and clarity with continued use How Deriva-BPO Gel Works Deriva-BPO Gel's effectiveness comes from the complementary actions of its two active ingredients: Adapalene is a retinoid that binds to specific retinoic acid receptors in skin cells. It normalizes the way skin cells mature and shed, helping to prevent dead cells and oil from clogging pores in the first place. Because it works on comedones before they become visible pimples, its main benefit is preventive — stopping new breakouts from forming rather than only treating existing ones. Benzoyl peroxide works through a different mechanism, releasing oxygen within the pore to create an environment where acne-causing bacteria cannot survive. It also has a mild exfoliating (keratolytic) effect, helping to clear away dead skin cells and excess oil from the surface. Used together, adapalene addresses the formation of new acne while benzoyl peroxide addresses existing bacterial overgrowth and inflammation — giving the combination broader coverage than either ingredient alone. How to Use Deriva-BPO Gel Cleanse the skin with a gentle, non-soap cleanser before application. Dry completely. Apply only to clean, fully dry skin to reduce irritation. Apply a thin layer to the affected area once daily, generally in the evening. Avoid sensitive areas, including the eyes, lips, corners of the nose, and mucous membranes. Wash your hands before and after applying the gel. Do not apply to broken, cut, sunburned, or eczematous skin. Use sunscreen daily. Both adapalene and benzoyl peroxide can increase skin sensitivity to sunlight, so a broad-spectrum, non-comedogenic sunscreen is essential during treatment. Avoid combining with other topical anti-acne agents (such as additional retinoids, benzoyl peroxide products, or tretinoin) unless specifically directed by your doctor, as this can significantly increase irritation. Results typically take several weeks to become noticeable, and it's common for mild irritation or a temporary "purging" phase to occur during the first two to four weeks as the skin adjusts. Consistent use is generally required for at least 8–12 weeks to properly assess effectiveness. Possible Side Effects Most side effects associated with Deriva-BPO Gel are localized to the skin and tend to improve as the skin builds tolerance: Burning or stinging sensation Skin redness (erythema) Dryness and scaling Local irritation or itching Skin peeling Less commonly, more pronounced reactions such as rash, blistering, swelling, or hives can occur and should be reported to a doctor promptly, especially if symptoms are severe or don't improve over time. Precautions and Who Should Avoid It Deriva-BPO Gel should be avoided or used only under medical guidance in the following situations: Allergy to adapalene, benzoyl peroxide, or any other ingredient in the formula Children under 9 years of age, as safety and efficacy have not been established Pregnancy — animal studies have shown potential harm to a developing fetus, so use during pregnancy is generally not recommended Broken, sunburned, or irritated skin in the treatment area Consult a doctor before use if you: Have any other skin conditions Are pregnant, planning to become pregnant, or breastfeeding (breastfeeding is generally considered lower risk, but medical advice is still recommended) Are using other topical or oral acne treatments Benzoyl peroxide may also cause bleaching of hair, clothing, and fabrics, so it's best to let the gel dry fully before contact with fabric. Storage Instructions Store below 25°C in a cool, dry place, away from direct sunlight Do not refrigerate Keep away from bathrooms, sinks, and areas with high heat or humidity Store out of reach of children Do not use after the expiry date printed on the packaging Why Choose Deriva-BPO Gel For patients dealing with a combination of comedonal and inflammatory acne, Deriva-BPO Gel offers the convenience of a dual-action formula in a single daily application, rather than requiring two separate products layered in sequence. Its once-daily use, established ingredient profile, and broad indication for ages 9 and up make it a commonly prescribed option for managing mild to moderate acne over the long term. This product description is intended for general informational purposes only and does not constitute medical advice. Deriva-BPO Gel is a prescription-only medication and should be used solely under the guidance of a qualified healthcare provider.