Sertagress 50 mg Tablet is an effective SSRI drug that has sertraline hydrochloride in it to treat premature ejaculation, depression & anxiety disorders. It works by changing serotonin transmission in the brain, which in turn slowly controls mood, emotional balance, anxiety response and ejaculatory latency. Aside from its common uses in psychiatry, sertraline is also known to delay ejaculation and is a secondary candidate for premature ejaculation management documented in literature. Key Features About Product Sertagress 50 mg Tablet Drug class Selective Serotonin Reuptake Inhibitor (SSRI) Chemical class Tetrahydronaphthalenamine Product Details Composition Active Ingredient: Sertraline Hydrochloride Inactive Ingredients: Microcrystalline cellulose Sodium starch glycolate Hydroxypropyl cellulose Magnesium stearate Formulation Oral Tablet Packaging Blister Pack Pack size 10*10 Dosage 50 mg Used For Premature Ejaculation Major Depressive Disorder Anxiety Disorders Manufacturer La Renon Healthcare Pvt. Ltd. Shelf Life 2-3 years Storage Store in a cool, dry place away from sunlight at a room temperature that’s ranging between 68°F and 77°F. Keep out of reach of children and pets. How does the Sertagress 50 mg tablet work? Sertagress 50 mg Tablet works by selectively blocking the reuptake transporter for serotonin at the neuronal synapse, allowing more serotonin to remain active between nerve cells. This heightened serotonergic tone is what underlies its antidepressant and anti-anxiety effects. In relation to ejaculatory control, elevated serotonin activity in spinal and brainstem pathways is thought to raise the threshold needed to trigger ejaculation. Uses Sertagress 50 mg Tablet is generally used for the following: Premature ejaculation Depressive disorders Generalized anxiety, panic disorder, social anxiety, and obsessive-compulsive disorder Dosage Guidance Any individual should speak with their healthcare provider before starting to take Sertagress 50 mg, but here are a couple guidelines that can be kept in mind: The Sertagress 50 mg tablet should be swallowed intact. One should avoid crushing or splitting the tablet. Sertagress 50 mg may be administered with or without meals. To be effective for premature ejaculation, Sertagress 50 mg has to be taken on a regular basis rather than taking it on-demand. Sertagress 50 mg is best taken at a fixed time each day to support steady blood levels. Possible Side Effects Abdominal discomfort Appetite fluctuations Sleep disturbances Headache Nausea or upset stomach Irritability or restlessness Lightheadedness Excessive drowsiness Muscle tremors Reduced concentration Rapid heartbeat Musculoskeletal pain (e.g., back pain) Drug Interactions Pairing diuretic medications, also known as ‘water’ tablets, with Sertagress 50 mg can carry a risk of developing low sodium levels, which can cause health complications. Combining migraine medications like triptans with Sertagress 50 mg can potentially lead to too much serotonin in the body. If you’re taking diabetes medications like insulin or sulfonylureas, then taking them with sertraline can increase the risk of experiencing a drop in blood sugar since sertraline increases insulin sensitivity. When Sertagress is combined with blood-thinning medications like warfarin, it can increase an individual’s risk of bleeding. Combining Sertagress 50 mg with monoamine oxidase inhibitors (MAOIs) can potentially lead to an overload of serotonin in an individual’s body. Pharmacokinetic Profile Reaches maximum blood concentration within roughly 4.5–8.4 hours post-dose. Elimination half-life averages around 26 hours, with steady-state concentration typically achieved after about a week of consistent dosing. Sertraline’s metabolism occurs through CYP3A4, CYP2C19, and CYP2B6 enzyme systems. Sertagress 50 mg is largely unaffected by food intake. Excreted through both renal and fecal pathways in comparable proportions. Safety Precautions Medical consultation advised for those with hepatic or renal conditions, bipolar disorder, or a seizure history. Alcohol intake should be limited or avoided during treatment. Not to be combined with MAOIs or other serotonin-affecting drugs. Use during pregnancy or breastfeeding requires professional evaluation, as safety data remains limited. Conclusion Sertagress 50 mg Tablet delivers sertraline, an SSRI that enhances central serotonin activity by inhibiting its reuptake. It is primarily used in mood and anxiety disorders but its serotonergic action is also the reason for its off-label use to delay ejaculation. The response and tolerability may vary from person to person, and therefore, one should consult a medical professional before starting the treatment for any of the indications. FAQs #sp-ea-46696 .spcollapsing { height: 0; overflow: hidden; transition-property: height;transition-duration: 300ms;}#sp-ea-46696.sp-easy-accordion>.sp-ea-single {margin-bottom: 25px; border: 1px solid #e2e2e2; }#sp-ea-46696.sp-easy-accordion>.sp-ea-single>.ea-header a {color: #0a0a0a;}#sp-ea-46696.sp-easy-accordion>.sp-ea-single>.sp-collapse>.ea-body {background: #ffffff; color: #0a0a0a;}#sp-ea-46696.sp-easy-accordion>.sp-ea-single {background: #ffffff;}#sp-ea-46696.sp-easy-accordion>.sp-ea-single>.ea-header a .ea-expand-icon { float: right; color: #0a0a0a;font-size: 16px;}#sp-ea-46696.sp-easy-accordion>.sp-ea-single>.ea-header a .ea-expand-icon {margin-right: 0;} 1) Is combining Sertagress 50 mg tablets with other drugs safe? You can do that, but only under your physician’s guidance. Certain combinations, particularly with MAOIs or other serotonergic drugs, can trigger the serotonin syndrome. 2) Can I drive after I have taken Sertagress 50 mg? It is generally not advised to drive or operate any heavy machinery just when an individual has started taking Sertagress 50 mg. You should wait and see how your body reacts since you could experience some dizziness. 3) Which medications can I not take when I’m consuming Sertagress 50 mg? Medications that fluctuate your serotonin levels like MAOIs or other antidepressants should be highly avoided when you’re taking sertraline. Other than that, you should speak with your healthcare provider about any other medications you should avoid. 4) How should I store Sertagress 50 mg safely? You should ideally store Sertagress 50 mg in a cool, dry place and away from moisture and direct sunlight. 5) Will I become dependent on Sertagress 50 mg? Sertagress 50 mg isn’t necessarily a habit-forming medication. 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" } },{ "@type": "Question", "name": "3) Which medications can I not take when I’m consuming Sertagress 50 mg?", "acceptedAnswer": { "@type": "Answer", "text": "Medications that fluctuate your serotonin levels like MAOIs or other antidepressants should be highly avoided when you’re taking sertraline. Other than that, you should speak with your healthcare provider about any other medications you should avoid." } },{ "@type": "Question", "name": "4) How should I store Sertagress 50 mg safely?", "acceptedAnswer": { "@type": "Answer", "text": "You should ideally store Sertagress 50 mg in a cool, dry place and away from moisture and direct sunlight. " } },{ "@type": "Question", "name": "5) Will I become dependent on Sertagress 50 mg?", "acceptedAnswer": { "@type": "Answer", "text": "Sertagress 50 mg isn’t necessarily a habit-forming medication. However, if you do stop taking it abruptly then you might experience some withdrawal symptoms. " } }] }