Doxoves® – STEALTH Liposomal Doxorubicin HCl (2.0mg/mL)

Description Doxoves® – PEGylated Liposomal Doxorubicin HCl (2.0mg/mL) Doxorubicin HCl is loaded into PEGylated liposomes with ammonium gradient by the active loading approach. It is comparable to the commercial product DOXIL®/Caelyx® at 2.0mg/mL drug concentration. The liposomes are prepared to high quality with consistent lot-lot characteristics. Narrow particle size distribution and high drug encapsulation efficiency. Product For Research only and NOT for Human Use Specifications Lipid composition: HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol) Lipid concentration: 20.0 mM Doxorubicin HCl: 2.0 mg/mL Encapsulation efficiency: > 95% (typically 98%) Loading battery: 250 mM ammonium sulfate Mean particle size: 85 nm (80 – 90 nm) External solution: 10% sucrose, 10 mM histidine, pH 6.5 Shelf-life: 6 months, storage: 2-8 degree C HSPC: hydrogenated phosphatidylcholine (Soy) CHOL: cholesterol mPEG2000-DSPE: 18:0 PEG2000 PE:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]