Fasted State Simulated Intestinal Fluid (FaSSIF) Powder Version BZ551

Fasted State Simulated Intestinal Fluid (FaSSIF) Dried Powder BZ551 Product Code: BZ551 Manufacturer: Biochemazone Available Pack Sizes for Making: 100 mL, 200 mL, 500 mL, 1000 mL Custom Bulk Quantities Available Product Overview Biochemazone Fasted State Simulated Intestinal Fluid (FaSSIF) Dried Powder BZ551 is a laboratory-formulated powdered medium designed to simulate the physiological composition and biorelevant conditions of the human small intestine under fasted-state conditions. This dry-format formulation allows convenient storage, transportation, and preparation of fresh simulated intestinal fluid prior to experimental use. The formulation is specifically developed to mimic the intestinal environment encountered in the upper gastrointestinal tract during the fasted state, including relevant bile salt content, phospholipid composition, buffering capacity, surface activity, and physiological pH conditions. This makes it highly suitable for pharmaceutical dissolution studies, oral drug delivery research, bioavailability assessment, and biopharmaceutical testing applications. Prepared using high-purity analytical-grade components, this standardized dried powder formulation provides excellent reproducibility and consistency for in vitro and preclinical studies. Upon reconstitution with purified water, the solution simulates intestinal fluid conditions relevant to solubility enhancement, dissolution behavior, permeability assessment, lipid-based formulation testing, and oral dosage form performance. BZ551 is widely used in oral drug formulation development, dissolution and release testing, bioaccessibility studies, lipid formulation evaluation, and biorelevant media testing. The formulation contains no preservatives and may also be customized for specific pH ranges, bile salt concentrations, surfactant systems, or specialized gastrointestinal simulation requirements depending on research applications. Key Features & Benefits ✅ Simulated Fasted-State Intestinal Environment – Designed to mimic physiological intestinal fluid conditions during fasting ✅ Dried Powder Format – Convenient storage and preparation of fresh media ✅ Preservative-Free Formulation – Suitable for sensitive research applications ✅ Biorelevant Composition – Mimics intestinal bile salt and phospholipid environment ✅ Physiological pH Simulation – Suitable for gastrointestinal dissolution studies ✅ Reproducible & Standardized – Ideal for comparative laboratory applications ✅ High-Purity Components – Prepared using analytical-grade raw materials ✅ Freshly Reconstituted Medium – Enhances experimental consistency and stability ✅ Ready-to-Prepare Formulation – Simple reconstitution for laboratory use Applications 🧪 Pharmaceutical & Drug Delivery Research Oral drug dissolution and release studies Solubility and bioavailability enhancement testing Lipid-based drug delivery system evaluation Preclinical & Biomedical Studies Gastrointestinal environment simulation Permeability and absorption assessment Controlled-release oral formulation studies 🔬 Biopharmaceutical & Analytical Research Biorelevant dissolution testing Supersaturation and precipitation studies Comparative formulation performance evaluation 🧬 Drug Development & Formulation Studies pH-dependent oral formulation assessment BCS classification support studies Amorphous and poorly soluble drug evaluation Typical Properties Appearance: Off-white to white free-flowing powder Reconstituted Appearance: Clear to slightly opalescent solution pH (after reconstitution): Physiological fasted-state intestinal pH range Solubility: Water soluble upon reconstitution Composition: Buffered intestinal electrolyte, bile salt, and phospholipid formulation, Pathogen Free Preservatives: None Buffering Capacity: Physiologically balanced intestinal buffering system Format: Dried powder preparation Storage & Stability Storage Temperature: 2–30 °C recommended Shelf Life: 12–24 months (sealed container) Shipping: Stable at room temperature Customization Options pH adjustment for specific gastrointestinal studies Customized bile salt and phospholipid concentrations Surfactant and lipid composition modifications Fed-state simulation modifications available upon request Species-specific or study-specific intestinal simulation customization Ordering Information BZ551 is available in standard laboratory sizes or OEM/bulk supply formats. 📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request 📧 Email: info@biochemazone.com 🌐 Website: Biochemazone ⚠️ For research, education, and in vitro testing only. Not for human or animal use