DUTCH Complete + DNA Health

DUTCH Complete The DUTCH Complete provides a comprehensive assessment of sex hormone metabolism and adrenal function using dried urine sampling across the day. The panel measures parent hormones and downstream metabolites alongside the diurnal pattern of free cortisol and markers of melatonin metabolism, offering detailed insight into hormone production, clearance and circadian rhythm patterns. In women, this type of profiling may be clinically relevant in contexts such as menstrual irregularities, premenstrual symptoms, menopausal transition, sleep disturbance or hormone replacement therapy monitoring. In men, it may support evaluation of fatigue, changes in mood or libido, altered body composition or age-related shifts in androgen balance. Inclusion of additional organic acid and oxidative stress markers enables broader consideration of metabolic and lifestyle factors that may influence hormonal regulation. Results are interpreted alongside clinical presentation, lifestyle patterns and other laboratory findings. Reviewing hormone metabolite patterns over time can help practitioners build a more personalised picture of endocrine function and support discussions around nutrition, lifestyle and therapeutic strategies. Indications Women Fatigue or low energy: Persistent tiredness that may relate to adrenal or sex hormone imbalance. Low mood or depression: Changes in emotional wellbeing or motivation linked to hormonal fluctuations. Reduced libido: Decline in sexual desire or satisfaction possibly influenced by oestrogen or testosterone levels. Premenstrual symptoms: PMS, irritability or mood swings occurring before menstruation. Menopausal changes: Hot flushes, sleep disruption or other signs of hormonal transition. Weight gain: Gradual or unexplained weight increase that may relate to changes in metabolism or hormone balance. Men Fatigue or low energy: Ongoing tiredness or reduced stamina possibly linked to hormone levels. Low mood or depression: Persistent low mood or lack of motivation that may correspond with testosterone or cortisol imbalance. Reduced sex drive: Lower libido or sexual performance potentially influenced by changes in androgen activity. Sleep disturbance: Difficulty falling asleep or staying asleep associated with cortisol rhythm. Hair loss: Gradual thinning or changes in hair pattern possibly linked with hormone variation. Weight gain: Increased abdominal or overall body weight that may reflect hormonal shifts. Practical Specimen requirements: Dried urine sample Average processing time: 18 ±4 days Restriction: This test is not available for patients below 12 years of age. DNA Health DNA Health® tests for genetic variations that are known to have a significant effect on health and susceptibility to chronic diseases. DNA Health reports on key biological pathways that govern overall health, and helps understand how genetic weaknesses in these pathways may increase predisposition to chronic diseases of lifestyle. Clinical value Can be viewed as a ‘foundation to health’ test and is therefore appropriate for any individual seeking to improve their health outcomes, be it those who already suffer health complaints such as chronic fatigue, gut issues, cardiovascular disease, or insulin resistance, or those who are concerned about a family history of a chronic disease of lifestyle. The test is also valuable for those who would like to optimise health outcomes and refine their health routine with a targeted approach to diet, lifestyle and nutraceuticals The report provides The level of impact of any genetic variants identified An explanation of their impact on health Appropriate nutritional and lifestyle recommendations The results are divided in sections of key metabolic function, so that genetic weaknesses and strengths within a functional area can be easily identified. Assessment of Over 35 genes involved in key metabolic processes: Lipid metabolism Methylation Detoxification Oxidative stress Inflammation Insulin resistance Bone health Iron metabolism Food responsiveness, including salt, alcohol & Caffeine sensitivity, bitter taste, lactose & gluten intolerance Vitamin metabolism