Selank ICCC

WHAT IS SELANK PEPTIDE? The peptide Selank has been labeled as an “anti-anxiety” peptide and has shown improvement in learning, memory, cognition, depression, weakness, and overall energy. BENEFITS OF SELANK While most prescription drugs come with unwanted side effects, studies have shown that Selank has no negative side effects or risk of addiction. Both Tuftsin and Selank have shown the ability to reduce anxiety and increase serotonin levels in animal models. Additional benefits of Selank include: Improved anxiety Enhanced learning Improved memory Stabilizes enkephalins in the blood, counteracting the stress response Aid in alcohol withdrawal Helps prevent weight gain and reduce cholesterol Additionally, Selank can strengthen immune function by increasing IL-6 in blood cells. IL-6 is an inflammatory protein believed to help fight off infections. It can also stimulate the release of interferons, which are anti-viral molecules. WHAT IS SELANK? Selank belongs to a class of molecules called synthetic peptides. It was developed by combining a peptide called tuftsin with another sequence that improves its molecular stability. Tuftsin is naturally involved in immune function and forms part of the natural antibody IgG. Selank was developed at the Institute of Molecular Genetics in cooperation with the V.V. Zakusov Research Institute of Pharmacology (Russian Academy of Medical Sciences) along with the nootropic drug Semax, sometimes referred to as its "cousin" peptide. Selank has been approved in Russia for the treatment of generalized anxiety disorder (GAD) and as a nootropic. In clinical trials, Selank has shown to provide a sustained nootropic and anxiolytic effect, which is useful for treating GAD. HOW DO YOU USE SELANK? Selank is used as a nasal spray. When taken orally, it is digested by the stomach and less effective. Inhaling it allows it to be absorbed directly into the bloodstream and reach the brain more effectively. The typical dosage is one spray in each nostril daily. RESEARCH & CLINICAL TRIALS Clinical trials have shown that Selank provides a sustained nootropic and anxiolytic effect, which is useful for treating generalized anxiety disorder (GAD). Unlike traditional anxiety treatments like benzodiazepines, Selank has no sedating or cognitive side effects and does not cause addiction or withdrawal issues. Some key studies include: Zozulia AA, Neznamov GG, Siuniakov TS, Kost NV, Gabaeva MV, Sokolov OIu, Serebriakova EV, Siranchieva OA, Andriushenko AV, Telesheva ES, Siuniakov SA, Smulevich AB, Miasoedov NF, Seredenin SB. "Efficacy and possible mechanisms of action of a new peptide anxiolytic Selank in the therapy of generalized anxiety disorders and neurasthenia." Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(4):38-48. Medvedev VE, Tereshchenko ON, Israelian AIu, Chobanu IK, Kost NV, Sokolov OIu, Miasoedov NF. "A comparison of the anxiolytic effect and tolerability of Selank and phenazepam in the treatment of anxiety disorders." Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114(7):17-22. Medvedev VE, Tereshchenko ON, Kost NV, Ter-Israelyan AY, Gushanskaya EV, Chobanu IK, Sokolov OY, Myasoedov NF. "Optimization of the treatment of anxiety disorders with Selank." Zh Nevrol Psikhiatr Im S S Korsakova. 2015;115(6):33-40. doi: 10.17116/jnevro20151156133-40. Uchakina ON, Uchakin PN, Miasoedov NF, Andreeva LA, Shcherbenko VE, Mezentseva MV, Gabaeva MV, Sokolov OIu, Zozulia AA, Ershov FI. "Immunomodulatory effects of Selank in patients with anxiety-asthenic disorders." Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(5):71-75. Mjasoedov NF1, Andreeva LA, Grigorjeva ME, Obergan TY, Shubina TA, Lyapina LA. "The influence of Selank on the parameters of the hemostasis system, lipid profile, and blood sugar level in the course of experimental metabolic syndrome." Dokl Biol Sci. 2014 Sep;458:267-70. doi: 10.1134/S0012496614050020. While the evidence is still limited, some of these studies suggest that Selank may be effective in curbing anxiety and providing other health benefits. However, further research is needed to monitor its long-term effectiveness and safety.