IGF-1LR3

IGF-1 LR3 is a synthetic analog of native IGF-1 designed for research applications. It features an arginine substitution at position 3 (Arg3) and an extended peptide sequence, modifications frequently used in laboratory settings to examine stability, receptor interaction, and anabolic signaling pathways. Research Modifications Increased stability and extended half-life in vitro Enhanced IGF-1 receptor binding affinity Altered anabolic signaling compared to native IGF-1 In preclinical and in vitro studies, IGF-1 LR3 is used to investigate: Binding interactions with IGF-1 receptors on muscle, tendon, ligament, and bone cells PI3K/Akt/mTOR signaling pathways associated with: Protein synthesis Cellular proliferation Tissue-repair modeling Glucose-uptake and insulin-sensitivity pathways in cellular models