Dopamine receptor D2 (DRD2 or D2R) antibody

Anti-Dopamine receptor D2 (DRD2 or D2R) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). There are five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3, and D4 receptors are members of the D2-like family. Dopamine receptor D2, also known as D2R, is encoded by the DRD2 gene in human. D2 receptors are coupled to the Gi subtype of G protein. This G protein-coupled receptor inhibits adenylyl cyclase activity. The dopamine D2 receptor is the main receptor for most antipsychotic drugs.