Potassium Chloride

High-Purity Potassium Chloride for Scientific Applications IBI potassium chloride is used primarily as a crucial in-organic salt to mimic the ion concentration of human blood plasma in Phosphate-Buffered-Saline (PBS). In a standard 1X PBS formulation, KCl is present at a concentration of 2.7mM (or 0.2g/L) alongside Nacl, Na2PO4 and KH2PO4 to maintain osmotic balance and physiological pH. Physiological Mimicry KCl provides a low concentration of potassium, ensuring the buffer remains isotonic with human tissues and cells, preventing lysis or shrinkage. Compatibility Issues KCl can cause precipitation when interacting with SDS in SDS-PAGE Gels, so it is often omitted (using only sodium-based salts) when working with protein samples intended for electrophoresis.